MTFR1L - mitochondrial fission regulator 1 like Gene

Also Known as FAM54B; MST116; MSTP116; HYST1888

Species: Homo sapiens

Gene Type: protein coding
Gene ID: 56181

About MTFR1L

This gene has 23 transcripts (splice variants), 209 orthologues and 2 paralogues. Ubiquitous expression in heart (RPKM 46.8), adrenal (RPKM 39.4) and 25 other tissues.

Summary

Predicted to be involved in aerobic respiration and mitochondrial fission. Predicted to be active in mitochondrion. [provided by Alliance of Genome Resources, Apr 2022]

MTFR1L Products (4)

mRNA Protein Name
NM_001099625.2 NP_001093095.1 mitochondrial fission regulator 1-like isoform a
NM_001099626.2 NP_001093096.1 mitochondrial fission regulator 1-like isoform a
NM_001099627.2 NP_001093097.1 mitochondrial fission regulator 1-like isoform b
NM_019557.6 NP_062457.3 mitochondrial fission regulator 1-like isoform a

Gene Ontology

  • Molecular Function
Molecular Function GO Annotation Evidence Références Source
enables protein binding IPI
IPI: Inferred from physical interaction
25416956 GOA
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern

MTFR1L Protein Structure

Mito_fiss_reg

Mito_fiss_reg: Mitochondrial fission regulator (9 - 254)

  • 0
  • 100
  • 200
  • 292 a.a.
Protein Preferred Names Protein Names

mitochondrial fission regulator 1-like

  • family with sequence similarity 54 member B

MTFR1L Protein-protein interaction Information

Type
Protein Name Protein ID Interactor Interactor Species Interactor ID Detection Method Références
Intra
MTFR1L Q9H019 ANKRD11 Homo sapiens X5D778
Validated Y2H
32296183
Intra
MTFR1L Q9H019 ARMC1 Homo sapiens Q9NVT9
Y2H Array
31515488
Intra
MTFR1L Q9H019 ARMC1 Homo sapiens Q9NVT9
Y2H Prey Pooling
26871637
Intra
MTFR1L Q9H019 ARMC1 Homo sapiens Q9NVT9
Validated Y2H
26871637
Intra
MTFR1L Q9H019 ARMC1 Homo sapiens Q9NVT9
Y2H Array
26871637
Intra
MTFR1L Q9H019 CNOT2 Homo sapiens Q9NZN8
Validated Y2H
32296183
Intra
MTFR1L Q9H019 MAGEA12 Homo sapiens P43365
Y2H Prey Pooling
25416956
Intra
MTFR1L Q9H019 MAGEA12 Homo sapiens P43365
Y2H Prey Pooling
26871637
Intra
MTFR1L Q9H019 MAGEA12 Homo sapiens P43365
Validated Y2H
26871637
Intra
MTFR1L Q9H019 MAGEA12 Homo sapiens P43365
Y2H Array
25416956
Intra
MTFR1L Q9H019 MAGEA12 Homo sapiens P43365
Y2H Array
26871637
Intra
MTFR1L Q9H019 AIRIM Homo sapiens Q9NX04
Validated Y2H
32296183
Cross: Cross-species interaction Intra: Intraspecies interaction

Related Diseases

Diseases Alias
Combined Oxidative Phosphorylation Deficiency 7

  • COXPD7

  • Combined Oxidative Phosphorylation Defect Type 7

  • Severe C12orf65-Related Combined Oxidative Phosphorylation Defect

  • Severe C12orf65-Related Coxpd

  • Combined Oxidative Phosphorylation Deficiency, Type 7
Diseases Alias
Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

Related Agents

  • Pre-clinical Phase

Pre-clinical Phase

Bioactive Molecules (1)
Cat. No. Nom du produit
Effect
Pureté
Rare Diseases
HY-RS08770 MTFR1L Human Pre-designed siRNA Set A Pre-designed Set / Unkown

Orthologs Information

Species Symbol Source ID
Rattus norvegicus MTFR1L RGD RGD:1305453
Felis catus MTFR1L VGNC VGNC:80284
Macaca mulatta MTFR1L VGNC VGNC:75036
Bos taurus MTFR1L VGNC VGNC:31727
Mus musculus MTFR1L MGD MGI:1924074
Canis familiaris MTFR1L VGNC VGNC:43469
Others MTFR1L NCBI