GLX481372
GLX481372 is a NADPH Oxidase (NOX) inhibitor. GLX481372 potently inhibits NOX4/5 activities with IC50 values of 0.68 and 0.57 μM. GLX481372 also has weak inhibitory activity against NOX1, NOX2, and NOX3, with IC50 values of 7, 16 and 3.2 μM respectively. GLX481372 can inhibit ROS production. GLX481372 can be used for the researches of inflammation, cardiovascular and metabolic disease, such as diabetes.
Nos produits utilisent uniquement pour la recherche. Nous ne vendons pas aux patients.
- CAS No.: 1990478-58-4
- Formule: C23H29N7
- Masse moléculaire:403.52
-
Stockage:
Please store the product under the recommended conditions in the Certificate of Analysis.
To place orders, for customer services and technical support, please contact: MedChemExpress USA
Tel: 609-228-6898 E-mail: [email protected] [email protected]
-
Activité biologique
-
Chemical Information
- Pureté et documentation
- Références
-
Help & FAQs
Activité biologique
|
NOX5 0.57 μM (IC50) |
NOX4 0.68 μM (IC50) |
NOX3 3.2 μM (IC50) |
NOX1 7 μM (IC50) |
NOX2 16 μM (IC50) |
Chemical Information
-
CAS No. 1990478-58-4
-
Masse moléculaire 403.52
-
Formule C23H29N7
-
SMILES
CC1=CC(NC2=NC(N)=NC(CN3CCN(CC3)C4=CC=C(C)C=C4)=N2)=CC=C1C
-
Livraison
Room temperature in continental US; may vary elsewhere.
-
Stockage
Please store the product under the recommended conditions in the Certificate of Analysis.
Pureté et documentation
Références
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
GLX481372 Related Classifications
HY-148936 Related Classifications
Powered by Bioz