HJP 272
HJP 272 is a selective endothelin peptide A (ETA) receptor antagonist with an IC50 of 37.01 nM. . HJP 272 can be used for the researches of pulmonary arterial hypertension, fibrosis, renal failure and cancer.
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- CAS No.: 1072467-37-8
- Formule: C28H23NO8
- Masse moléculaire:501.48
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Stockage:
Please store the product under the recommended conditions in the Certificate of Analysis.
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Activité biologique
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Chemical Information
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Activité biologique
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ETA 37.01 nM (IC50) |
ETB 15602.3 nM (IC50) |
HJP 272 (Compound 41) acts as an ETA-selective receptor antagonist in HEK293T cells, with an ETA IC50 of 37.01 nM and 421-fold selectivity over the ETB receptor[1].
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
Chemical Information
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CAS No. 1072467-37-8
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Masse moléculaire 501.48
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Formule C28H23NO8
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SMILES
O=C(C1=CC=CC(CC2=C(C(O)=O)N(CC3=CC4=C(C=C3CC)OCO4)C5=CC=C(O)C=C5C2=O)=C1)O
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Livraison
Room temperature in continental US; may vary elsewhere.
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Stockage
Please store the product under the recommended conditions in the Certificate of Analysis.
Pureté et documentation
Références
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
HJP 272 Related Classifications
HY-183141 Related Classifications
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