Iminodiacetic acid
Based on 1 Customer Validation
Iminodiacetic acid is a metal ion chelator targeting Cr6+, Cd2+, Ni2+, and Pb2+. Iminodiacetic acid selectively and irreversibly binds metal ions through the coordination of carboxyl and imino groups, reduces the toxicity of metal ions and promotes their adsorption and separation. Iminodiacetic acid has the functions of heavy metal ion removal and coordination complex stabilization. Iminodiacetic acid is often used in environmental pollution control (such as heavy metal adsorption in water) and coordination chemistry (such as metal ion detection and separation) research.
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- Pureté : 99.87%
- CAS No.: 142-73-4
- Formule: C4H7NO4
- Masse moléculaire:133.10
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Stockage:
Store at room temperature 3 years.
In solvent -80°C, 2 years , -20°C, 1 year
Activité biologique
Description
In Vitro
In the heavy metal ion adsorption experiment, Iminodiacetic acid (200 mg resin; 3.5 h) achieves removal efficiencies of 99.7%, 65%, 59% and 28% for Cr6+, Ni2+, Pb2+ and Cd2+ respectively[1].
Iminodiacetic acid (1 mM; 24 h) forms a 1:1:1 ternary complex with Pd2+ in the coordination chemistry experiment and was stable[2].
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
Essai clinique
| NCT Number | Sponsor | Condition | Start Date |
Phase
|
|---|---|---|---|---|
| NCT01329991 | 2011-05 | PHASE1 |
Chemical Information
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CAS No. 142-73-4
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Appearance Solid
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Masse moléculaire 133.10
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Formule C4H7NO4
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Color White to off-white
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SMILES
O=C(O)CNCC(O)=O
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Structure Classification
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Initial Source
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Livraison
Room temperature in continental US; may vary elsewhere.
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Stockage
Store at room temperature 3 years
In solvent -80°C 2 years -20°C 1 year
Solvant et solubilité
In Vitro:
H2O : 5 mg/mL (37.57 mM; Need ultrasonic)
DMSO : < 1 mg/mL (insoluble or slightly soluble)
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 2 years; -20°C, 1 year. When stored at -80°C, please use it within 2 years. When stored at -20°C, please use it within 1 year.
* Note: If you choose water as the stock solution, please dilute it to the working solution, then filter and sterilize it with a 0.22 μm filter before use.
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 2 years; -20°C, 1 year. When stored at -80°C, please use it within 2 years. When stored at -20°C, please use it within 1 year.
* Note: If you choose water as the stock solution, please dilute it to the working solution, then filter and sterilize it with a 0.22 μm filter before use.
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
In Vivo Dissolution Calculator
Please enter the basic information of animal experiments:
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Recommended: Prepare an additional quantity of animals to account for potential losses during experiments.
Working solution concentration: 0.22 mg/mL
Pureté et documentation
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Fiche technique (270 KB)
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SDS (394 KB)
- English - EN (394 KB)
- Français - FR (394 KB)
- Deutsch - DE (394 KB)
- Norwegian - NO (394 KB)
- Español - ES (394 KB)
- Swedish - SV (394 KB)
- Italian - IT (394 KB)
- Korean - KR (394 KB)
- Portuguese - PT (394 KB)
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Instruction de manipulation (2659 KB)
Références
[1]. Misra RK, et al. Iminodiacetic acid functionalized cation exchange resin for adsorptive removal of Cr(VI), Cd(II), Ni(II) and Pb(II) from their aqueous solutions. J Hazard Mater. 2011 Jan 30;185(2-3):1508-12. [Content Brief]
[2]. Shihui Lin, et al. Explore potential plasma biomarkers of acute respiratory distress syndrome (ARDS) using GC-MS metabolomics analysis. Clin Biochem. 2019 Apr;66:49-56. [Content Brief]
Complete Stock Solution Preparation Table
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 2 years; -20°C, 1 year. When stored at -80°C, please use it within 2 years. When stored at -20°C, please use it within 1 year.
| Optional Solvent | Concentration Solvent Mass | 1 mg | 5 mg | 10 mg | 25 mg |
|---|---|---|---|---|---|
| H2O | 1 mM | 7.5131 mL | 37.5657 mL | 75.1315 mL | 187.8287 mL |
| 5 mM | 1.5026 mL | 7.5131 mL | 15.0263 mL | 37.5657 mL | |
| 10 mM | 0.7513 mL | 3.7566 mL | 7.5131 mL | 18.7829 mL | |
| 15 mM | 0.5009 mL | 2.5044 mL | 5.0088 mL | 12.5219 mL | |
| 20 mM | 0.3757 mL | 1.8783 mL | 3.7566 mL | 9.3914 mL | |
| 25 mM | 0.3005 mL | 1.5026 mL | 3.0053 mL | 7.5131 mL | |
| 30 mM | 0.2504 mL | 1.2522 mL | 2.5044 mL | 6.2610 mL |
* Note: If you choose water as the stock solution, please dilute it to the working solution, then filter and sterilize it with a 0.22 μm filter before use.