K1833
K1833 is a hrAChE inhibitor/reactivator, with an IC50 of 58 μM. K1833 also shows high inhibition (IC50=0.57μM) and low reactivation for hrBChE.
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- Formule: C26H28BBr2F2N7O2
- Masse moléculaire:679.16
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Stockage:
Please store the product under the recommended conditions in the Certificate of Analysis.
Activité biologique
Description
IC50 & Target
[1]|
hAChE 58 μM (IC50) |
hBCHE 0.57 μM (IC50) |
Chemical Information
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Masse moléculaire 679.16
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Formule C26H28BBr2F2N7O2
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SMILES
FB1(F)N2C=CC=C2C(NCCNC(C3=CC=[N+](CCC[N+]4=CC=C(/C=N/O)C=C4)C=C3)=O)=C5C=CC=[N]15.[Br-].[Br-]
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Livraison
Room temperature in continental US; may vary elsewhere.
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Stockage
Please store the product under the recommended conditions in the Certificate of Analysis.
Protocole
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Cell Cytotoxicity Assay
Cytotoxicity assays are usually based on the assessment of cell membrane damage, which can also be indirectly detected by measuring cell viability. Detection methods include MTT assay, CKK-8 assay, LDH assay and ATP assay, etc.
Pureté et documentation
Références
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)