Explore how anti-Aβ therapy is reshaping the AD treatment landscape, the rationale for multi-pathology combination strategies, and advances in biomarker-guided precision treatment.
Centres d’apprentissage
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Beyond Aβ Clearance: Exploring Multi-Pathology Strategies in Alzheimer’s Disease -
Engineering mRNA Therapeutics: Molecular Design, Targeted Delivery, and Translational Challenges Explore advances in mRNA molecular design and targeted delivery, emerging non-LNP platforms, and key translational challenges shaping broader applications beyond vaccines. -
Beyond Target Competition: Payload Chemistry and the Next Stage of ADC Design Explore the rise of TOP1i-class payloads, the impact of payload–linker design on therapeutic window and developability, and how novel payloads are expanding ADC design boundaries. -
Molecular Glues: Rewiring Protein Interactions for Targeted Degradation Review the evolution of molecular glues from serendipitous discovery to rational design, highlighting how emerging targets and advances in screening, proteomics, structural biology, and AI are expanding the druggable proteome.
