m-PEG13-NHS ester
Based on 1 Customer Validation
m-PEG13-NHS ester is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs.
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- Pureté: 95.0%
- CAS No.: 3063847-98-0
- Formule: C32H59NO17
- Masse moléculaire:729.81
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Stockage:
-20°C, sealed storage, away from moisture and light
* In solvent : -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture and light)
Voir tous les produits spécifiques à Isoform PROTAC Linkers
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Activité biologique
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PEGs |
Alkyl/ether |
PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins[1].
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
Chemical Information
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CAS No. 3063847-98-0
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Appearance Oil
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Masse moléculaire 729.81
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Formule C32H59NO17
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Color Colorless to off-white
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SMILES
COCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCC(ON1C(CCC1=O)=O)=O
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Livraison
Room temperature in continental US; may vary elsewhere.
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Stockage
-20°C, sealed storage, away from moisture and light
* In solvent : -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture and light)
Solvant et solubilité
DMSO : 100 mg/mL (137.02 mM; Need ultrasonic; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture and light). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture and light). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
Pureté et documentation
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Fiche technique (274 KB)
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SDS (393 KB)
- English - EN (393 KB)
- Français - FR (393 KB)
- Deutsch - DE (393 KB)
- Norwegian - NO (393 KB)
- Español - ES (393 KB)
- Swedish - SV (393 KB)
- Italian - IT (393 KB)
- Korean - KR (393 KB)
- Portuguese - PT (393 KB)
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Instruction de manipulation (2659 KB)
Références
Complete Stock Solution Preparation Table
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture and light). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
| Optional Solvent | Concentration Solvent Mass | 1 mg | 5 mg | 10 mg | 25 mg |
|---|---|---|---|---|---|
| DMSO | 1 mM | 1.3702 mL | 6.8511 mL | 13.7022 mL | 34.2555 mL |
| 5 mM | 0.2740 mL | 1.3702 mL | 2.7404 mL | 6.8511 mL | |
| 10 mM | 0.1370 mL | 0.6851 mL | 1.3702 mL | 3.4255 mL | |
| 15 mM | 0.0913 mL | 0.4567 mL | 0.9135 mL | 2.2837 mL | |
| 20 mM | 0.0685 mL | 0.3426 mL | 0.6851 mL | 1.7128 mL | |
| 25 mM | 0.0548 mL | 0.2740 mL | 0.5481 mL | 1.3702 mL | |
| 30 mM | 0.0457 mL | 0.2284 mL | 0.4567 mL | 1.1418 mL | |
| 40 mM | 0.0343 mL | 0.1713 mL | 0.3426 mL | 0.8564 mL | |
| 50 mM | 0.0274 mL | 0.1370 mL | 0.2740 mL | 0.6851 mL | |
| 60 mM | 0.0228 mL | 0.1142 mL | 0.2284 mL | 0.5709 mL | |
| 80 mM | 0.0171 mL | 0.0856 mL | 0.1713 mL | 0.4282 mL | |
| 100 mM | 0.0137 mL | 0.0685 mL | 0.1370 mL | 0.3426 mL |