MDAN-21
MDAN-21 is a bivalent opioid ligand that contains both μ-opioid receptor agonists and δ-opioid receptor antagonists. MDAN-21 has a strong analgesic effect and does not produce tolerance in mouse studies. MDAN-21 can effectively inhibit the withdrawal of morphine dependent monkeys and alleviate abnormal pain in the study of rhesus monkeys. MDAN-21 can be used for the study of allodynia.
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- CAS No.: 873573-64-9
- Formule: C58H71N7O12
- Masse moléculaire:1058.22
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Stockage:
Please store the product under the recommended conditions in the Certificate of Analysis.
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Activité biologique
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Chemical Information
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Activité biologique
Description
IC50 & Target
[1]|
μ Opioid Receptor/MOR |
δ Opioid Receptor/DOR |
Chemical Information
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CAS No. 873573-64-9
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Masse moléculaire 1058.22
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Formule C58H71N7O12
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SMILES
O[C@]12[C@]34[C@](OC5=C(O)C=CC(C[C@@]2([H])N(CC4)CC6CC6)=C53)([H])C7=C(C8=CC=CC(NC(COCC(NCCCCCCCNC(COCC(N[C@@H]9[C@@]%10([H])[C@]%11%12C%13=C(C[C@](N(CC%12)C)([H])[C@@]%11(CC9)O)C=CC(O)=C%13O%10)=O)=O)=O)=O)=C8N7)C1
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Livraison
Room temperature in continental US; may vary elsewhere.
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Stockage
Please store the product under the recommended conditions in the Certificate of Analysis.
Pureté et documentation
Références
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
MDAN-21 Related Classifications
HY-178235 Related Classifications
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