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Cat. No.: HY-P5559

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ND1-YL2

Name: ND1-YL2
Brand: MedChemExpress
SKU: HY-P5559
Price: 1315.00 USD
Availability: InStock
Rating: 5 (1 reviews)

ND1-YL2 is a PROTAC that selectively degrades SRC-1 via the N-degron pathway. ND1-YL2 significantly inhibits cancer invasion and migration in vitro and in vivo. ND1-YL2 can be used in cancer research.

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CAS No.: 2582803-80-1
Formule: C₁₁₄H₁₈₉N₂₇O₂₈
Masse moléculaire:2385.88

Stockage:

Please store the product under the recommended conditions in the Certificate of Analysis.

ND1-YL2 Chemical Structure

CAS No.: 2582803-80-1

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Use of MCE Products

Fluorescent Dye

Strong Fluorescence Signal / Multi-Disciplinary Applications / High Fluorescence Specificity

Activité biologique
- Description
- IC₅₀ & Target
Chemical Information
Pureté et documentation
Références
Calculators
Help & FAQs
Classifications
Bioz

Activité biologique

Description

IC₅₀ & Target

SRC-1^[1].

Voir tous les produits spécifiques à Isoform PROTACs :

Chemical Information

CAS No. 2582803-80-1
Masse moléculaire 2385.88
Formule C₁₁₄H₁₈₉N₂₇O₂₈
Sequence

Arg-Leu-Ala-Ala-Ala-Ala-Leu-Leu-Pro-Pro-Thr-Glu-Gln-Asp-Leu-{S-2(4-Pentenyl)Ala}-Lys-Leu-{(Cyclohexyl)Ala}-{S-2(4-Pentenyl)Ala}-Tyr-NH2
Sequence Shortening

RLAAAALLPPTEQDL-{S-2(4-Pentenyl)Ala}-KL-{(Cyclohexyl)Ala}-{S-2(4-Pentenyl)Ala}-Y-NH2
Livraison

Room temperature in continental US; may vary elsewhere.
Stockage

Please store the product under the recommended conditions in the Certificate of Analysis.

Pureté et documentation

Select Batch:

Pureté: 99.98%

Assay: 99.98%

ee.: 99.98%

Fiche technique (259 KB)
COA (2659 KB)
Elemental Analysis Report (2659 KB)
HNMR (2659 KB)
CNMR (2659 KB)
RP-HPLC (2659 KB)
NP-HPLC (2659 KB)
MS (2659 KB)
LCMS (2659 KB)
IR (2659 KB)
GC (2659 KB)
OR (2659 KB)
SDS-PAGE (2659 KB)
SEC-HPLC (2659 KB)
Other Report (2659 KB)
Instruction de manipulation (2659 KB)

Références

[1]. Lee Y, et al. Targeted Degradation of Transcription Coactivator SRC-1 through the N-Degron Pathway. Angew Chem Int Ed Engl. 2020 Sep 28;59(40):17548-17555. [Content Brief]

Calculators

Calculateur de molarité

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

Mass Mass

Concentration Concentration

Volume Volume

Molecular Weight Molecular Weight

Calculateur de dilution

Concentration _(start) × Volume _(start) = Concentration _(final) × Volume _(final)

Concentration _(start) Concentration _(start)

Volume _(start) Volume _(start)

Concentration _(final) Concentration _(final)

Volume _(final) Volume _(final)

Help & FAQs

How should lyophilized recombinant proteins be reconstituted and stored?

1. Before opening the cap, centrifuge the vial at 13000 rpm for 20-30 seconds. This step will ensure that any lyophilized powder that may have adhered to the cap or walls is collected at the bottom of the vial, minimizing the risk of product loss.

Bioz

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100 mg

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Activité biologique
- Description
- IC₅₀ & Target
Chemical Information
Pureté et documentation
Références

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ND1-YL2

Voir tous les produits spécifiques à Isoform PROTACs