NTPDase2-IN-1
NTPDase2-IN-1 is a non-competitive, selective NTPDase2 inhibitor, with an IC50 of 0.04 μM against h-NTPDase2 and an IC50 of 2.27 μM against h-NTPDase8. NTPDase2-IN-1 is applicable for cancer-related research.
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- CAS No.: 2883147-47-3
- Formule: C24H20FN3OS2
- Masse moléculaire:449.56
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Stockage:
Please store the product under the recommended conditions in the Certificate of Analysis.
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Activité biologique
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Chemical Information
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Help & FAQs
Activité biologique
Description
IC50 & Target
[1]|
h-NTPDase-2 0.04 μM (IC50) |
h-NTPDase-8 2.27 μM (IC50) |
In Vitro
NTPDase2-IN-1 (Compound 5g) (100 μM; 15 min) exhibits an inhibition rate of 42% against recombinant h-NTPDase1 at a concentration of 100 μM[1].
NTPDase2-IN-1 (15 min) potently inhibits recombinant h-NTPDase2, with an IC50 value of 0.04 μM[1].
NTPDase2-IN-1 (100 μM; 15 min) inhibits 28% of recombinant h-NTPDase3 at a concentration of 100 μM[1].
NTPDase2-IN-1 (15 min) inhibits recombinant h-NTPDase8 with an IC50 value of 2.27 μM[1].
NTPDase2-IN-1 (0.02-0.08 μM) acts as a non-competitive inhibitor of recombinant h-NTPDase2, which reduces Vmax without altering Km[1].
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
Chemical Information
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CAS No. 2883147-47-3
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Masse moléculaire 449.56
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Formule C24H20FN3OS2
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SMILES
CC(C1=CC=C(C(F)=C1)C2=CC=CC=C2)C(NC3=NN=C(S3)SCC4=CC=CC=C4)=O
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Livraison
Room temperature in continental US; may vary elsewhere.
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Stockage
Please store the product under the recommended conditions in the Certificate of Analysis.
Pureté et documentation
Références
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
NTPDase2-IN-1 Related Classifications
HY-143288 Related Classifications
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