RU-39411
RU-39411 is a steroidal anti-estrogen with mixed estrogenic/antiestrogen activity. RU-39411 has shown inhibitory effects on cell growth in the MCF-7 breast cancer model, with the effect being correlated with its binding affinity to the estrogen receptor. RU-39411 was able to downregulate the estrogen binding capacity of cells, but did not reduce estrogen receptor mRNA levels, indicating that the grafting of its side chain prevents the antagonistic effects usually associated with steroidal estrogens. The administration of RU-39411 can promote the synthesis of progesterone receptors, further supporting its activity as an estrogen.
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- CAS No.: 120382-04-9
- Formule: C28H37NO3
- Masse moléculaire:435.60
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Stockage:
Please store the product under the recommended conditions in the Certificate of Analysis.
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Activité biologique
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Chemical Information
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Activité biologique
Description
Chemical Information
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CAS No. 120382-04-9
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Masse moléculaire 435.60
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Formule C28H37NO3
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SMILES
C[C@@]12[C@H](CC[C@]1([C@@]3(CCC4=C([C@]3([C@H](C2)C5=CC=C(C=C5)OCCN(C)C)[H])C=CC(O)=C4)[H])[H])O
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Livraison
Room temperature in continental US; may vary elsewhere.
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Stockage
Please store the product under the recommended conditions in the Certificate of Analysis.
Pureté et documentation
Références
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
RU-39411 Related Classifications
HY-117649 Related Classifications
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