Saussureamine C
Saussureamine C shows gastroprotective effect on acidified ethanol-induced gastric mucosal lesions in rats. Saussureamine C inhibits H274Y and N294S mutants and can be used for research of influenza virus infection. Saussureamine C can be isolated from the dried roots of Saussurea lappa Clarke.
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- CAS No.: 148245-83-4
- Formule: C19H26N2O5
- Masse moléculaire:362.42
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Stockage:
Please store the product under the recommended conditions in the Certificate of Analysis.
Activité biologique
Description
Cellular Effect
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Cell Line
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Type | Value | Description | References |
|---|---|---|---|---|
| Macrophage | IC50 |
16 μg/mL
Compound: 12
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Antiinflammatory activity in mouse macrophages assessed as LPS-induced nitric oxide production
Antiinflammatory activity in mouse macrophages assessed as LPS-induced nitric oxide production
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10.1039/C2MD20172K |
Chemical Information
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CAS No. 148245-83-4
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Masse moléculaire 362.42
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Formule C19H26N2O5
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SMILES
O=C(N)C[C@@H](C(O)=O)NC[C@H]1[C@@](CC2)([H])[C@]([C@@]3([H])C(CC[C@@]3([H])C2=C)=C)([H])OC1=O
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Structure Classification
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Livraison
Room temperature in continental US; may vary elsewhere.
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Stockage
Please store the product under the recommended conditions in the Certificate of Analysis.
Pureté et documentation
Références
[1]. Yoshikawa M, et al. Saussureamines A, B, C, D, and E, new anti-ulcer principles from Chinese Saussureae Radix. Chem Pharm Bull (Tokyo). 1993 Jan;41(1):214-6. [Content Brief]
[2]. Tou WI, et al. Residue-based design of small molecule inhibitor for H1N1, H5N1 and H7N1 mutants. J Mol Model. 2016 Jan;22(1):4. [Content Brief]
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)