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Cat. No.: HY-10437A

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Setileuton tosylate

(Synonyms: MK-0633 tosylate)

Setileuton tosylate is an inhibitor for 5-lipoxygenase, that inhibits the oxidation of arachidonic acid by recombinant human 5-LO, and the production of LTB4 in calcium ionophore-stimulated human whole blood, with IC₅₀ of 3.9 and 52 nM, respectively.

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CAS No.: 1137737-87-1
Formule: C₂₉H₂₅F₄N₃O₇S
Masse moléculaire:635.58

Stockage:

Please store the product under the recommended conditions in the Certificate of Analysis.

Data Sheet (265 KB)

Setileuton tosylate Chemical Structure

CAS No.: 1137737-87-1

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Use of MCE Products

Fluorescent Dye

Strong Fluorescence Signal / Multi-Disciplinary Applications / High Fluorescence Specificity

Activité biologique

Description

Voir tous les produits spécifiques à Isoform Lipoxygenase :

Chemical Information

CAS No. 1137737-87-1
Masse moléculaire 635.58
Formule C₂₉H₂₅F₄N₃O₇S
SMILES

O=S(O)(C1=CC=C(C=C1)C)=O.O=C2C=C(C3=CC=C(C=C3)F)C4=CC=C(CNC5=NN=C([C@](CC)(O)C(F)(F)F)O5)C=C4O2
Synonyms

MK-0633 tosylate
Livraison

Room temperature in continental US; may vary elsewhere.
Stockage

Please store the product under the recommended conditions in the Certificate of Analysis.

Pureté et documentation

Select Batch:

Pureté: 99.98%

Assay: 99.98%

ee.: 99.98%

Fiche technique (265 KB)
COA (2659 KB)
Elemental Analysis Report (2659 KB)
HNMR (2659 KB)
CNMR (2659 KB)
RP-HPLC (2659 KB)
NP-HPLC (2659 KB)
MS (2659 KB)
LCMS (2659 KB)
IR (2659 KB)
GC (2659 KB)
OR (2659 KB)
SDS-PAGE (2659 KB)
SEC-HPLC (2659 KB)
Other Report (2659 KB)
Instruction de manipulation (2659 KB)

Références

[1]. Ducharme Y, et al., The discovery of setileuton, a potent and selective 5-lipoxygenase inhibitor. ACS Med Chem Lett. 2010 Apr 13;1(4):170-4. [Content Brief]

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Calculateur de molarité

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Molecular Weight Molecular Weight

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Help & FAQs

How should lyophilized recombinant proteins be reconstituted and stored?

1. Before opening the cap, centrifuge the vial at 13000 rpm for 20-30 seconds. This step will ensure that any lyophilized powder that may have adhered to the cap or walls is collected at the bottom of the vial, minimizing the risk of product loss.

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100 mg

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Setileuton tosylate

Voir tous les produits spécifiques à Isoform Lipoxygenase

Activité biologique

Chemical Information

Pureté et documentation

Références

Calculators

Help & FAQs

Setileuton tosylate Related Classifications

HY-10437A Related Classifications