Setileuton tosylate
Setileuton tosylate is an inhibitor for 5-lipoxygenase, that inhibits the oxidation of arachidonic acid by recombinant human 5-LO, and the production of LTB4 in calcium ionophore-stimulated human whole blood, with IC50 of 3.9 and 52 nM, respectively.
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- CAS No.: 1137737-87-1
- Formule: C29H25F4N3O7S
- Masse moléculaire:635.58
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Stockage:
Please store the product under the recommended conditions in the Certificate of Analysis.
Activité biologique
Description
Chemical Information
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CAS No. 1137737-87-1
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Masse moléculaire 635.58
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Formule C29H25F4N3O7S
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SMILES
O=S(O)(C1=CC=C(C=C1)C)=O.O=C2C=C(C3=CC=C(C=C3)F)C4=CC=C(CNC5=NN=C([C@](CC)(O)C(F)(F)F)O5)C=C4O2
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Synonyms
MK-0633 tosylate
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Livraison
Room temperature in continental US; may vary elsewhere.
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Stockage
Please store the product under the recommended conditions in the Certificate of Analysis.
Protocole
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Cell Cytotoxicity Assay
Cytotoxicity assays are usually based on the assessment of cell membrane damage, which can also be indirectly detected by measuring cell viability. Detection methods include MTT assay, CKK-8 assay, LDH assay and ATP assay, etc.
Pureté et documentation
Références
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)