Sinopodophylline B
Sinopodophylline B (compound 2) is a flavonoid glycoside compound that is cytotoxic to breast cancer cells. For example, the IC50 of Sinopodophylline B is 1.5 μM (T47D) and 44.2 μM (MDA-MB-231), respectively.
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- CAS No.: 1369959-47-6
- Formule: C21H20O7
- Masse moléculaire:384.38
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Stockage:
Please store the product under the recommended conditions in the Certificate of Analysis.
Activité biologique
Description
Cellular Effect
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Cell Line
|
Type | Value | Description | References |
|---|---|---|---|---|
| Hep 3B2 | IC50 |
2.39 μM
Compound: 22
|
Cytotoxicity against human Hep3B cells assessed as inhibition of cell proliferation incubated for 48 hrs by MTT assay
Cytotoxicity against human Hep3B cells assessed as inhibition of cell proliferation incubated for 48 hrs by MTT assay
|
[PMID: 36549116] |
| HepG2 | IC50 |
>50 μM
Compound: 22
|
Cytotoxicity against human HepG2 cells assessed as inhibition of cell proliferation incubated for 48 hrs by MTT assay
Cytotoxicity against human HepG2 cells assessed as inhibition of cell proliferation incubated for 48 hrs by MTT assay
|
[PMID: 36549116] |
Chemical Information
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CAS No. 1369959-47-6
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Masse moléculaire 384.38
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Formule C21H20O7
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SMILES
COC1=C(C2=CC=C(O)C(O)=C2)OC3=C(C/C=C(C)\C)C(O)=CC(O)=C3C1=O
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Structure Classification
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Initial Source
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Livraison
Room temperature in continental US; may vary elsewhere.
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Stockage
Please store the product under the recommended conditions in the Certificate of Analysis.
Pureté et documentation
Références
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)