sSPhos Pd G2
Based on 1 Customer Validation
sSPhos Pd G2 is a water-soluble palladium catalyst. sSPhos Pd G2 mediates Suzuki-Miyaura cross-coupling reactions for protein biotinylation and on-DNA reactions, thereby enabling robust gel-based ABPP using iodocysteine-reactive probes rather than bromo- or chloro-substituted probes.
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- Pureté : 95.0%
- CAS No.: 2375242-78-5
- Formule: C38H44ClNNaO5PPdS
- Masse moléculaire:822.66
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Stockage:
4°C, sealed storage, away from moisture
* In solvent : -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture)
To place orders, for customer services and technical support, please contact: MedChemExpress USA
Tel: 609-228-6898 E-mail: [email protected] [email protected]
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Activité biologique
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Chemical Information
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Solvant et solubilité
- Pureté et documentation
- Références
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Help & FAQs
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Activité biologique
Description
In Vitro
sSPhos Pd G2 enables on-DNA glycal-based Suzuki-Miyaura coupling of DNA head pieces with glycal boronates at 90 °C, yielding glycal-DNA conjugates 20a-20s[1].
sSPhos-Pd-G2 mediates DNA-compatible hydroxycarbonylation of aryl iodides and bromides with moderate to very good conversions, whereas aryl chlorides react with poor to moderate conversions[4].
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
Chemical Information
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CAS No. 2375242-78-5
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Appearance Solid
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Masse moléculaire 822.66
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Formule C38H44ClNNaO5PPdS
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Color Light brown to brown
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SMILES
Cl[Pd]1([P](C2CCCCC2)(C3CCCCC3)C4=CC=CC=C4C5=C(OC)C=CC(S(=O)(O[Na])=O)=C5OC)C6=CC=CC=C6C7=CC=CC=C7[NH2]1
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Livraison
Room temperature in continental US; may vary elsewhere.
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Stockage
4°C, sealed storage, away from moisture
* In solvent : -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture)
Solvant et solubilité
In Vitro:
DMSO : 10 mg/mL (12.16 mM; Need ultrasonic; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
Pureté et documentation
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Fiche technique (286 KB)
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SDS (394 KB)
- English - EN (394 KB)
- Français - FR (394 KB)
- Deutsch - DE (394 KB)
- Norwegian - NO (394 KB)
- Español - ES (394 KB)
- Swedish - SV (394 KB)
- Italian - IT (394 KB)
- Korean - KR (394 KB)
- Portuguese - PT (394 KB)
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Instruction de manipulation (2659 KB)
Références
Complete Stock Solution Preparation Table
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
| Optional Solvent | Concentration Solvent Mass | 1 mg | 5 mg | 10 mg | 25 mg |
|---|---|---|---|---|---|
| DMSO | 1 mM | 1.2156 mL | 6.0778 mL | 12.1557 mL | 30.3892 mL |
| 5 mM | 0.2431 mL | 1.2156 mL | 2.4311 mL | 6.0778 mL | |
| 10 mM | 0.1216 mL | 0.6078 mL | 1.2156 mL | 3.0389 mL |
sSPhos Pd G2 Related Classifications
HY-W583317 Related Classifications
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Keywords
- sSPhos Pd G2
- 2375242-78-5
- sSPhos Pd G 2
- sSPhos Pd G-2
- Biochemical Assay Reagents
- Endogenous Metabolite
- DNA-compatible
- DNA-encoded chemical library synthesis
- Suzuki-Miyaura cross-coupling
- aryl halides
- cysteine-reactive probe
- gel-based ABPP
- glycal-DNA conjugates
- hydroxycarbonylation
- on-DNA reactions
- protein biotinylation
- Inhibitor
- inhibitor
- inhibit