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Cat. No.: HY-172114

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Thalidomide-4-piperidineacetaldehyde

Thalidomide-4-piperidineacetaldehyde is an E3 ligase ligand and linker conjugate and can be used to synthesize PROTAC H122 (HY-172113).

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CAS No.: 2222115-36-6
Formule: C₂₀H₂₁N₃O₅
Masse moléculaire:383.40

Stockage:

Please store the product under the recommended conditions in the Certificate of Analysis.

Data Sheet (264 KB)

Thalidomide-4-piperidineacetaldehyde Chemical Structure

CAS No.: 2222115-36-6

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Strong Fluorescence Signal / Multi-Disciplinary Applications / High Fluorescence Specificity

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Description

Thalidomide-4-piperidineacetaldehyde is an E3 ligase ligand and linker conjugate and can be used to synthesize PROTAC H122 (HY-172113)^[1].

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Chemical Information

CAS No. 2222115-36-6
Masse moléculaire 383.40
Formule C₂₀H₂₁N₃O₅
SMILES

O=C(CC1)NC(C1N(C2=O)C(C(C2=C3)=CC=C3N(CC4)CCC4CC=O)=O)=O
Livraison

Room temperature in continental US; may vary elsewhere.
Stockage

Please store the product under the recommended conditions in the Certificate of Analysis.

Pureté et documentation

Select Batch:

Pureté: 99.98%

Assay: 99.98%

ee.: 99.98%

Fiche technique (264 KB)
COA (2659 KB)
Elemental Analysis Report (2659 KB)
HNMR (2659 KB)
CNMR (2659 KB)
RP-HPLC (2659 KB)
NP-HPLC (2659 KB)
MS (2659 KB)
LCMS (2659 KB)
IR (2659 KB)
GC (2659 KB)
OR (2659 KB)
SDS-PAGE (2659 KB)
SEC-HPLC (2659 KB)
Other Report (2659 KB)
Instruction de manipulation (2659 KB)

Références

[1]. Lu Y, et al. Selective Degradation of TEADs by a PROTAC Molecule Exhibited Robust Anticancer Efficacy In Vitro and In Vivo. J Med Chem. 2025 Jan 13. [Content Brief]

Calculators

Calculateur de molarité

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

Mass Mass

Concentration Concentration

Volume Volume

Molecular Weight Molecular Weight

Calculateur de dilution

Concentration _(start) × Volume _(start) = Concentration _(final) × Volume _(final)

Concentration _(start) Concentration _(start)

Volume _(start) Volume _(start)

Concentration _(final) Concentration _(final)

Volume _(final) Volume _(final)

Help & FAQs

How should lyophilized recombinant proteins be reconstituted and stored?

1. Before opening the cap, centrifuge the vial at 13000 rpm for 20-30 seconds. This step will ensure that any lyophilized powder that may have adhered to the cap or walls is collected at the bottom of the vial, minimizing the risk of product loss.

Keywords

Thalidomide-4-piperidineacetaldehyde

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Thalidomide-4-piperidineacetaldehyde

Voir tous les produits spécifiques à Isoform E3 Ligase Ligand-Linker Conjugates

Activité biologique

Chemical Information

Pureté et documentation

Références

Calculators

Help & FAQs

Thalidomide-4-piperidineacetaldehyde Related Classifications

HY-172114 Related Classifications