TMC-205
TMC-205 is a natural fungal metabolite with antiproliferative activity against cancer cell lines. TMC-205 is a transcriptional up-regulator of SV40 promoter.
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- CAS No.: 403646-00-4
- Formule: C14H13NO2
- Masse moléculaire:227.26
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Stockage:
Please store the product under the recommended conditions in the Certificate of Analysis.
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Activité biologique
Description
IC50 & Target
[1]|
Microbial Metabolite |
Cellular Effect
|
Cell Line
|
Type | Value | Description | References |
|---|---|---|---|---|
| HCT-116 | GI50 |
68 μM
Compound: 1, TMC-205
|
Antiproliferative activity against human HCT116 cells assessed as growth inhibition after 72 hrs by MTS assay
Antiproliferative activity against human HCT116 cells assessed as growth inhibition after 72 hrs by MTS assay
|
[PMID: 25147604] |
Chemical Information
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CAS No. 403646-00-4
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Masse moléculaire 227.26
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Formule C14H13NO2
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SMILES
O=C(C1=CNC2=C1C=CC(/C=C/C(C)=C)=C2)O
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Structure Classification
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Initial Source
an unidentified fungus.
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Livraison
Room temperature in continental US; may vary elsewhere.
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Stockage
Please store the product under the recommended conditions in the Certificate of Analysis.
Pureté et documentation
Références
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)