VcMMAE-Eribulin
Based on 1 Customer Validation
VcMMAE-Eribulin is a Drug-Linker Conjugates for ADC, which is composed of a linker and a toxic molecule MMAE (HY-15162) (Microtubule inhibitor) and Eribulin (HY-13442) (Microtubule inhibitor). VcMMAE-Eribulin can be used for ADC synthesis.
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- Pureté : 98.87%
- CAS No.: 2760408-69-1
- Formule: C131H194N18O33
- Masse moléculaire:2549.04
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Stockage:
-20°C, sealed storage, away from moisture and light
* In solvent : -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture and light)
To place orders, for customer services and technical support, please contact: MedChemExpress USA
Tel: 609-228-6898 E-mail: [email protected] [email protected]
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Activité biologique
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Chemical Information
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Solvant et solubilité
- Pureté et documentation
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Help & FAQs
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Activité biologique
Description
IC50 & Target
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Dual payloads |
Chemical Information
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CAS No. 2760408-69-1
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Appearance Solid
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Masse moléculaire 2549.04
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Formule C131H194N18O33
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Color White to off-white
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SMILES
C=C1C[C@@]2([H])O[C@@]1([H])CC[C@]3([H])O[C@](C([C@H](C)C3)=C)([H])C[C@@]4([H])[C@]([C@@H](OC)[C@@H](C[C@H](O)CNC(OCC5=CC=C(NC([C@H](CCCNC(N)=O)NC([C@H](C(C)C)NC(CC(C(N[C@@H](C(C)C)C(N[C@@H](CCCNC(N)=O)C(NC6=CC=C(COC(N(C)[C@@H](C(C)C)C(N[C@@H](C(C)C)C(N([C@@H]([C@@H](C)CC)[C@H](OC)CC(N7[C@@]([C@H](OC)[C@@H](C)C(N[C@H](C)[C@@H](O)C8=CC=CC=C8)=O)([H])CCC7)=O)C)=O)=O)=O)C=C6)=O)=O)=O)NC(CCCCCN9C(C=CC9=O)=O)=O)=O)=O)=O)C=C5)=O)O4)([H])CC(C[C@]%10([H])O[C@]%11([H])[C@]%12([H])O[C@@]%13(O[C@@]%14([H])[C@@](O[C@]%12([H])[C@@]%14([H])O[C@@]%11([H])CC%10)([H])C%13)CC2)=O
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Synonyms
SMP13432
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Livraison
Room temperature in continental US; may vary elsewhere.
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Stockage
-20°C, sealed storage, away from moisture and light
* In solvent : -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture and light)
Solvant et solubilité
In Vitro:
DMSO : ≥ 100 mg/mL (39.23 mM; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)
* "≥" means soluble, but saturation unknown.
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture and light). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture and light). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
Pureté et documentation
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Fiche technique (248 KB)
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SDS (252 KB)
- English - EN (252 KB)
- Français - FR (252 KB)
- Deutsch - DE (252 KB)
- Norwegian - NO (252 KB)
- Español - ES (252 KB)
- Swedish - SV (252 KB)
- Italian - IT (252 KB)
- Korean - KR (252 KB)
- Portuguese - PT (252 KB)
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Instruction de manipulation (2659 KB)
Complete Stock Solution Preparation Table
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture and light). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
| Optional Solvent | Concentration Solvent Mass | 1 mg | 5 mg | 10 mg | 25 mg |
|---|---|---|---|---|---|
| DMSO | 1 mM | 0.3923 mL | 1.9615 mL | 3.9230 mL | 9.8076 mL |
| 5 mM | 0.0785 mL | 0.3923 mL | 0.7846 mL | 1.9615 mL | |
| 10 mM | 0.0392 mL | 0.1962 mL | 0.3923 mL | 0.9808 mL | |
| 15 mM | 0.0262 mL | 0.1308 mL | 0.2615 mL | 0.6538 mL | |
| 20 mM | 0.0196 mL | 0.0981 mL | 0.1962 mL | 0.4904 mL | |
| 25 mM | 0.0157 mL | 0.0785 mL | 0.1569 mL | 0.3923 mL | |
| 30 mM | 0.0131 mL | 0.0654 mL | 0.1308 mL | 0.3269 mL |
VcMMAE-Eribulin Related Classifications
HY-164837 Related Classifications
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