Calcium L-Threonate
Based on 1 publication(s) in Google Scholar
Calcium L-Threonate, a calcium aldonate, is a calcium supplement. Calcium L-Threonate can be used for the study of osteoporosis.
For research use only. We do not sell to patients.
- Purity: 98.0%
- CAS No.: 70753-61-6
- Formula: C4H8O5.1/2Ca
- Molecular Weight:156.14
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Storage:
4°C, sealed storage, away from moisture
* In solvent : -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture)
To place orders, for customer services and technical support, please contact: MedChemExpress USA
Tel: 609-228-6898 E-mail: [email protected] [email protected]
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Biological Activity
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Chemical Information
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Solvent & Solubility
- Purity & Documentation
- References
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Help & FAQs
Publications Citing Use of MedChemExpress (MCE) Calcium L-Threonate
MoreAll Endogenous Metabolite Isoforms
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Biological Activity
Calcium L-Threonate inhibits the bone resorption of osteoclasts in vitro[1].
Calcium L-Threonate (0-1,000 mg%) stimulated Ascorbic acid (1.25 mg%) uptake in a dose-dependent manner in human T-lymphoma cells[2].
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
Chemical Information
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CAS No. 70753-61-6
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Appearance Solid
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Molecular Weight 156.14
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Formula C4H8O5.1/2Ca
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Color White to off-white
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SMILES
O=C(O)[C@H](O)[C@@H](O)CO.[1/2].[Ca]
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Structure Classification
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Initial Source
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
4°C, sealed storage, away from moisture
* In solvent : -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture)
Publications (1)
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Journal Impact Factor
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Most Recent
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Nature
2025 Jul;643(8070):192-200. PMID: 39695227
Solvent & Solubility
H2O : 5 mg/mL (32.02 mM; ultrasonic and warming and heat to 60°C)
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
* Note: If you choose water as the stock solution, please dilute it to the working solution, then filter and sterilize it with a 0.22 μm filter before use.
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
* Note: If you choose water as the stock solution, please dilute it to the working solution, then filter and sterilize it with a 0.22 μm filter before use.
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
Purity & Documentation
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Data Sheet (273 KB)
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SDS (393 KB)
- English - EN (393 KB)
- Français - FR (393 KB)
- Deutsch - DE (393 KB)
- Norwegian - NO (393 KB)
- Español - ES (393 KB)
- Swedish - SV (393 KB)
- Italian - IT (393 KB)
- Korean - KR (393 KB)
- Portuguese - PT (393 KB)
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Handling Instructions (2659 KB)
References
[1]. Calcium L-Threonate, et al. Pharmacokinetics and safety of calcium L-threonate in healthy volunteers after single and multiple oral administrations. Acta Pharmacol Sin. 2011 Dec;32(12):1555-60. [Content Brief]
[2]. Calcium L-Threonate, et al. Stimulatory action of calcium L-threonate on ascorbic acid uptake by a human T-lymphoma cell line. Life Sci. 1991;49(19):1377-81. [Content Brief]
Complete Stock Solution Preparation Table
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
| Optional Solvent | Concentration Solvent Mass | 1 mg | 5 mg | 10 mg | 25 mg |
|---|---|---|---|---|---|
| H2O | 1 mM | 6.4045 mL | 32.0225 mL | 64.0451 mL | 160.1127 mL |
| 5 mM | 1.2809 mL | 6.4045 mL | 12.8090 mL | 32.0225 mL | |
| 10 mM | 0.6405 mL | 3.2023 mL | 6.4045 mL | 16.0113 mL | |
| 15 mM | 0.4270 mL | 2.1348 mL | 4.2697 mL | 10.6742 mL | |
| 20 mM | 0.3202 mL | 1.6011 mL | 3.2023 mL | 8.0056 mL | |
| 25 mM | 0.2562 mL | 1.2809 mL | 2.5618 mL | 6.4045 mL | |
| 30 mM | 0.2135 mL | 1.0674 mL | 2.1348 mL | 5.3371 mL |
* Note: If you choose water as the stock solution, please dilute it to the working solution, then filter and sterilize it with a 0.22 μm filter before use.
Calcium L-Threonate Related Classifications
HY-W009208 Related Classifications
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