1000160-97-3
1000160-97-3
Chemical Structure
Indacaterol xinafoate
- CAS No.: 1000160-97-3
- Formula:C35H36N2O6
- Molecular Weight:580.67
InChIKey: FPVXKDOIWQBXBE-FTBISJDPSA-N
SMILES: OC1=C(C(O)=O)C=CC2=C1C=CC=C2.CCC(C=C(C3)C(CC3NC[C@@H](C4=C5C(NC(C=C5)=O)=C(C=C4)O)O)=C6)=C6CC
Biological Activity: Indacaterol xinafoate is an orally active long-acting β2-adrenergic agonist (LABA) with bronchodilatory effect. Indacaterol inhibits NF-κB activity in a β-arrestin2-dependent manner, preventing further lung damage and improving lung function in COPD (chronic obstructive pulmonary disorder). Indacaterol xinafoate can be utilized in asthma research[1] [2].
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Indacaterol xinafoate | Indacaterol xinafoate is an orally active long-acting β2-adrenergic agonist (LABA) with bronchodilatory effect. Indacaterol inhibits NF-κB activity in a β-arrestin2-dependent manner, preventing further lung damage and improving lung function in COPD (chronic obstructive pulmonary disorder). Indacaterol xinafoate can be utilized in asthma research . | |||||||||||||||||||||
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References
- [1]. van Z, et al. Mometasone/Indacaterol/Glycopyrronium (MF/IND/GLY) and MF/IND at Different MF Strengths versus Fluticasone Propionate/Salmeterol Xinafoate (FLU/SAL) and FLU/SAL+ Tiotropium in Patients with Asthma. J Asthma Allergy. 2023 Jan 20;16:123-134. [Content Brief]
- [2]. Lee SU, et al. Indacaterol inhibits tumor cell invasiveness and MMP-9 expression by suppressing IKK/NF-κB activation. Mol Cells. 2014 Aug;37(8):585-91. [Content Brief]
