Indacaterol xinafoate
Based on 5 publication(s) in Google Scholar
Indacaterol xinafoate is an orally active long-acting β2-adrenergic agonist (LABA) with bronchodilatory effect. Indacaterol inhibits NF-κB activity in a β-arrestin2-dependent manner, preventing further lung damage and improving lung function in COPD (chronic obstructive pulmonary disorder). Indacaterol xinafoate can be utilized in asthma research .
For research use only. We do not sell to patients.
- CAS No.: 1000160-97-3
- Formula: C35H36N2O6
- Molecular Weight:580.67
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Storage:
Please store the product under the recommended conditions in the Certificate of Analysis.
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Biological Activity
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Chemical Information
- Purity & Documentation
- References
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Publications Citing Use of MedChemExpress (MCE) Indacaterol xinafoate
MoreAll Adrenergic Receptor Isoforms
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Biological Activity
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β2 adrenoceptor |
Chemical Information
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CAS No. 1000160-97-3
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Molecular Weight 580.67
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Formula C35H36N2O6
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SMILES
OC1=C(C(O)=O)C=CC2=C1C=CC=C2.CCC(C=C(C3)C(CC3NC[C@@H](C4=C5C(NC(C=C5)=O)=C(C=C4)O)O)=C6)=C6CC
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
Please store the product under the recommended conditions in the Certificate of Analysis.
Publications (5)
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Journal Impact Factor
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Most Recent
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Pharmaceutics
Development of an In Vitro System to Study the Interactions of Aerosolized Drugs with Pulmonary Mucus. [Abstract]2020 Feb 11;12(2):145. PMID: 32053877 -
J Chromatogr A
2024 Feb 22:1717:464696. PMID: 38310699 -
Drug Test Anal
High-throughput liquid chromatography tandem mass spectrometry assay as initial testing procedure for analysis of total urinary fraction. [Abstract]2021 Feb;13(2):283-298. PMID: 32852861 -
J Neuroimmunol
Mechanism underlying β2-AR agonist-mediated phenotypic conversion of LPS-activated microglial cells. [Abstract]2019 Jul 15:332:37-48. PMID: 30933849 -
bioRxiv
2025 May 29:2025.05.28.656715. PMID: 40502188
Purity & Documentation
References
[1]. van Z, et al. Mometasone/Indacaterol/Glycopyrronium (MF/IND/GLY) and MF/IND at Different MF Strengths versus Fluticasone Propionate/Salmeterol Xinafoate (FLU/SAL) and FLU/SAL+ Tiotropium in Patients with Asthma. J Asthma Allergy. 2023 Jan 20;16:123-134. [Content Brief]
[2]. Lee SU, et al. Indacaterol inhibits tumor cell invasiveness and MMP-9 expression by suppressing IKK/NF-κB activation. Mol Cells. 2014 Aug;37(8):585-91. [Content Brief]
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
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