10025-73-7
Chemical Structure
Chromium chloride
- CAS No.: 10025-73-7
- Formula:CrCl3
- Molecular Weight:158.36
IUPAC Name: chromium(III) chloride
InChIKey: QSWDMMVNRMROPK-UHFFFAOYSA-K
SMILES: Cl[Cr](Cl)Cl
Biological Activity: Chromium chloride is a trivalent chromium compound and an essential trace mineral. Chromium chloride enhances insulin-stimulated GLUT4 translocation and glucose uptake in skeletal muscle. Chromium chloride regulates glucose and lipid metabolism, inhibits TNF-α secretion and oxidative stress in monocytes treated with high glucose or H2O2, and reverses hydrogen peroxide-induced cell growth inhibition. Chromium chloride reduces coronary and aortic lipid deposition and serum cholesterol levels in hypercholesterolemic rabbits. Chromium chloride can be used in research related to diabetes and cardiac atherosclerosis[1][2][3].
| Cat. No. | Product Name | Purity | Description | Pricing | |||||||||||||||||||
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Chromium chloride | 99.9% | Chromium chloride is a trivalent chromium compound and an essential trace mineral. Chromium chloride enhances insulin-stimulated GLUT4 translocation and glucose uptake in skeletal muscle. Chromium chloride regulates glucose and lipid metabolism, inhibits TNF-α secretion and oxidative stress in monocytes treated with high glucose or H2O2, and reverses hydrogen peroxide-induced cell growth inhibition. Chromium chloride reduces coronary and aortic lipid deposition and serum cholesterol levels in hypercholesterolemic rabbits. Chromium chloride can be used in research related to diabetes and cardiac atherosclerosis. | ||||||||||||||||||||
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- [1]. Doerner PG 3rd, et al. Chromium chloride increases insulin-stimulated glucose uptake in the perfused rat hindlimb. Acta Physiol (Oxf). 2014;212(3):205-213. [Content Brief]
- [2]. Jain SK, et al. Chromium chloride inhibits oxidative stress and TNF-alpha secretion caused by exposure to high glucose in cultured U937 monocytes. Biochem Biophys Res Commun. 2001;289(3):687-691. [Content Brief]
- [3]. Price Evans DA, et al. Chromium chloride administration causes a substantial reduction of coronary lipid deposits, aortic lipid deposits, and serum cholesterol concentration in rabbits. Biol Trace Elem Res. 2009;130(3):262-272. [Content Brief]
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