100874-08-6
100874-08-6
Chemical Structure
BMP signaling agonist sb4
- CAS No.: 100874-08-6
- Formula:C14H10BrNOS
- Molecular Weight:320.20
IUPAC Name: 2-((4-bromobenzyl)thio)benzo[d]oxazole
InChIKey: JDVOIBFEFVKUPL-UHFFFAOYSA-N
SMILES: BrC1=CC=C(CSC2=NC3=CC=CC=C3O2)C=C1
Biological Activity: BMP signaling agonist sb4 is a potent benzoxazole bone morphogenetic protein 4 (BMP4) signaling agonist with a EC50 value of 74 nM, activates BMP signaling by stabilizing intracellular p-SMAD-1/5/9. BMP signaling agonist sb4 activates BMP4 target genes (inhibitors of DNA binding,?Id1?and?Id3) canonical BMP signaling[1].
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BMP signaling agonist sb4 | 99.98% | BMP signaling agonist sb4 is a potent benzoxazole bone morphogenetic protein 4 (BMP4) signaling agonist with a EC50 value of 74 nM, activates BMP signaling by stabilizing intracellular p-SMAD-1/5/9. BMP signaling agonist sb4 activates BMP4 target genes (inhibitors of DNA binding,?Id1?and?Id3) canonical BMP signaling. | ||||||||||||||||||||
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Structural Analogs
-
Similarity Score 0.71
HY-161343HDL-16 -
Similarity Score 0.67
HY-103061Dehydro-ZINC39395747 -
Similarity Score 0.65
HY-163111Antibacterial agent 170 -
Similarity Score 0.64
![4-(Benzo[d]oxazol-2-yl)aniline Chemical Structure](//file.medchemexpress.com/product_pic/hy-w029411.gif)
HY-W0294114-(Benzo[d]oxazol-2-yl)aniline -
Similarity Score 0.61
HY-117121MeV-IN-1 -
Similarity Score 0.60
HY-161996IDO1-IN-25 -
Similarity Score 0.60
HY-124938ABC-1 -
Similarity Score 0.58
HY-W32422011β-HSD1-IN-10 -
Similarity Score 0.57
HY-B2141AR2-(phenylmethyl)-1H-Benzimidazole hydrochloride (1:1) (Standard) -
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![4-(Benzo[d]oxazol-2-yl)aniline Chemical Structure](http://file.medchemexpress.com/product_pic/hy-w029411.gif)
