101910-24-1
101910-24-1
Chemical Structure
REV 5901
- CAS No.: 101910-24-1
- Formula:C22H25NO2
- Molecular Weight:335.44
IUPAC Name: 1-(3-(quinolin-2-ylmethoxy)phenyl)hexan-1-ol
InChIKey: JRLOEMCOOZSCQP-UHFFFAOYSA-N
SMILES: OC(CCCCC)C1=CC=CC(OCC2=NC3=CC=CC=C3C=C2)=C1
Biological Activity: REV 5901 is a competitive and orally active antagonist of leukotriene receptor, with a Ki of 0.7 μM. REV 5901 is also a 5-lipoxygenase inhibitor. REV 5901 can be used for the research of asthma in which leukotriene release be involved. REV 5901 can be used for the study of colon carcinoma[1][2][3].
| Cat. No. | Product Name | Purity | Description | Pricing | |||||||||||||||||||
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REV 5901 | 99.9% | REV 5901 is a competitive and orally active antagonist of leukotriene receptor, with a Ki of 0.7 μM. REV 5901 is also a 5-lipoxygenase inhibitor. REV 5901 can be used for the research of asthma in which leukotriene release be involved. REV 5901 can be used for the study of colon carcinoma. | ||||||||||||||||||||
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References
- [1]. Inwegen RGV, et, al. REV 5901: an orally effective peptidoleukotriene antagonist, detailed biochemical/pharmacological profile. J Pharmacol Exp Ther. 1987 Apr;241(1):117-24. [Content Brief]
- [2]. Anderson G, et, al. Effects of REV 5901, a 5-lipoxygenase inhibitor and leukotriene antagonist, on pulmonary responses to platelet activating factor in the guinea-pig. Br J Pharmacol. 1988 Aug;94(4):1115-22. [Content Brief]
- [3]. Paskaš S, et al. Carborane-Based Analog of Rev-5901 Attenuates Growth of Colon Carcinoma In Vivo. Molecules. 2022 Jul 14;27(14):4503. [Content Brief]
Keywords
