102743-85-1
Chemical Structure
Biocytin hydrazide
- CAS No.: 102743-85-1
- Formula:C16H30N6O3S
- Molecular Weight:386.51
IUPAC Name: 1,1'-(oxybis(methylene))dipyrene
InChIKey: XSXHTPJCSHZYFJ-MNXVOIDGSA-N
SMILES: NNC([C@@H](N)CCCCNC(CCCC[C@H]1[C@]2([H])[C@](NC(N2)=O)([H])CS1)=O)=O
Biological Activity: Biocytin hydrazide is a long-chain biotin-containing hydrazide, serving as a biotin-derived active coupling reagent, selective labeling agent and biotinylating reagent. Biocytin hydrazide targets aldehyde, carboxyl, amino and guanidino groups to biotinylate glycoconjugates, K99 lectin, peptides and proteins through its hydrazide moiety, and achieves nonradioactive detection of sialic acid- and galactose-containing glycoconjugates via the avidin–biotin system[1][2][3].
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Biocytin hydrazide | 99.24% | Biocytin hydrazide is a long-chain biotin-containing hydrazide, serving as a biotin-derived active coupling reagent, selective labeling agent and biotinylating reagent. Biocytin hydrazide targets aldehyde, carboxyl, amino and guanidino groups to biotinylate glycoconjugates, K99 lectin, peptides and proteins through its hydrazide moiety, and achieves nonradioactive detection of sialic acid- and galactose-containing glycoconjugates via the avidin–biotin system. | ||||||||||||||||||||
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- [1]. Bayer EA, et al. Biocytin hydrazide--a selective label for sialic acids, galactose, and other sugars in glycoconjugates using avidin-biotin technology. Anal Biochem. 1988;170(2):271-281. [Content Brief]
- [2]. Ouadia A, et al. Detection of the ganglioside N-glycolyl-neuraminyl-lactosyl-ceramide by biotinylated Escherichia coli K99 lectin. Glycoconj J. 1992;9(1):21-26. [Content Brief]
- [3]. Lee BS. Biotinylation of Peptides/Proteins Using Biocytin Hydrazide. J Chin Chem Soc. 2007;54(2):541-548.
Keywords
