1044870-39-4
1044870-39-4
Chemical Structure
Apabetalone
Synonym(s): RVX-208; RVX000222
- CAS No.: 1044870-39-4
- Formula:C20H22N2O5
- Molecular Weight:370.40
IUPAC Name: 2-(4-(2-hydroxyethoxy)-3,5-dimethylphenyl)-5,7-dimethoxyquinazolin-4(3H)-one
InChIKey: NETXMUIMUZJUTB-UHFFFAOYSA-N
SMILES: COC1=CC(OC)=C(C(NC(C2=CC(C)=C(OCCO)C(C)=C2)=N3)=O)C3=C1
Biological Activity: Apabetalone (RVX-208) is an inhibitor of BET transcriptional regulators with selectivity for the second bromodomain. The IC50s are 87 μM and 0.51 μM for BD1 and BD2, respectively[1].
| Cat. No. | Product Name | Purity | Description | Pricing | |||||||||||||||||||
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Apabetalone | 99.34% | Apabetalone (RVX-208) is an inhibitor of BET transcriptional regulators with selectivity for the second bromodomain. The IC50s are 87 μM and 0.51 μM for BD1 and BD2, respectively. | ||||||||||||||||||||
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Apabetalone (Standard) | ≥98% | Apabetalone (Standard) is the analytical standard of Apabetalone. This product is intended for research and analytical applications. Apabetalone (RVX-208) is an inhibitor of BET transcriptional regulators with selectivity for the second bromodomain. The IC50s are 87 μM and 0.51 μM for BD1 and BD2, respectively. | ||||||||||||||||||||
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Structural Analogs
-
Similarity Score 0.82
HY-162514BBC0403 -
Similarity Score 0.82
HY-114504RVX-297 -
Similarity Score 0.61
HY-149087MR2938 -
Similarity Score 0.59
HY-178041BRD4-BD1/2-IN-3 -
Similarity Score 0.56
HY-150613PARP1/BRD4-IN-2 -
Similarity Score 0.53
HY-145260BRD4/CK2-IN-1 -
Similarity Score 0.48
HY-177268CHNQD-01426 -
Similarity Score 0.48
HY-154868MMP-13-IN-1 -
Similarity Score 0.47
HY-137918TGF-βRI inhibitor 3 -
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