1067892-47-0
Chemical Structure
Wortmannin-Rapamycin Conjugate 1
- CAS No.: 1067892-47-0
- Formula:C88H131N3O23
- Molecular Weight:1598.99
InChIKey: GVMCLKAVNVFURS-UXLLMVCWSA-N
SMILES: C[C@@]12C3=C(C(C(O)=C1/C(C(O[C@@H]2COC)=O)=C\N(C)CCCN(C)C)=O)[C@@]4([H])[C@](C[C@H]3OC(C)=O)([C@H](CC4)OC(CCCCCCC(O[C@H]5[C@@H](C[C@@H](CC5)C[C@H]([C@@]6([H])OC([C@@]7([H])N(CCCC7)C(C([C@@]8(O[C@](CC[C@H]8C)([H])C[C@@H](/C(C)=C/C=C/C=C/[C@H](C[C@H](C([C@@H]([C@@H](/C(C)=C/[C@H](C(C6)=O)C)O)OC)=O)C)C)OC)O)=O)=O)=O)C)OC)=O)=O)C
Biological Activity: Wortmannin-Rapamycin Conjugate 1 (compound 7c) is a furan ring-opened derivative of wortmannin-rapamycin conjugate with potent antitumor activities and a fine water solubility. Wortmannin-Rapamycin Conjugate 1 can inhibit the AKT phosphorylation in the tumor and can be used for cancer research[1].
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Wortmannin-Rapamycin Conjugate 1 | Wortmannin-Rapamycin Conjugate 1 (compound 7c) is a furan ring-opened derivative of wortmannin-rapamycin conjugate with potent antitumor activities and a fine water solubility. Wortmannin-Rapamycin Conjugate 1 can inhibit the AKT phosphorylation in the tumor and can be used for cancer research. | |||||||||||||||||||||
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Keywords
