1071135-06-2
1071135-06-2
Chemical Structure
PKC/PKD-IN-1
- CAS. Nr.: 1071135-06-2
- Formula:C23H28N6
- Molecular Weight:388.51
IUPAC Name: N-cyclohexyl-4-(1-(piperazin-1-yl)-2,6-naphthyridin-3-yl)pyridin-2-amine
InChIKey: DIZACSOTRSXCHC-UHFFFAOYSA-N
SMILES: C1(NC2CCCCC2)=NC=CC(C3=CC4=C(C(N5CCNCC5)=N3)C=CN=C4)=C1
Biological Activity: PKC/PKD-IN-1 (Compound 13C) is an orally active dual protein kinase C/D (PKC/PKD) inhibitor with an IC50 value of 0.6 nM for PKD1. PKC/PKD-IN-1 can attenuate high-salt diet-induced cardiac hypertrophy and can be used in the study of heart failure[1].
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PKC/PKD-IN-1 | 98.35% | PKC/PKD-IN-1 (Compound 13C) is an orally active dual protein kinase C/D (PKC/PKD) inhibitor with an IC50 value of 0.6 nM for PKD1. PKC/PKD-IN-1 can attenuate high-salt diet-induced cardiac hypertrophy and can be used in the study of heart failure. | ||||||||||||||||||||
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