1. Apoptosis
  2. PKD
  3. BPKDi

BPKDi is a potent bipyridyl PKD inhibitor with IC50s of 1 nM, 9 nM and 1 nM for PKD1, PKD2 and PKD3, respectively. BPKDi blocks signal-dependent phosphorylation and nuclear export of class IIa HDACs in cardiomyocytes.

For research use only. We do not sell to patients.

BPKDi Chemical Structure

BPKDi Chemical Structure

CAS No. : 1201673-28-0

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Description

BPKDi is a potent bipyridyl PKD inhibitor with IC50s of 1 nM, 9 nM and 1 nM for PKD1, PKD2 and PKD3, respectively. BPKDi blocks signal-dependent phosphorylation and nuclear export of class IIa HDACs in cardiomyocytes[1].

IC50 & Target[1]

PKD1

1 nM (IC50)

PKD2

9 nM (IC50)

PKD3

1 nM (IC50)

Molecular Weight

380.49

Formula

C21H28N6O

CAS No.
Appearance

Solid

Color

Off-white to light yellow

SMILES

O=C(N)C1=CC(C2=CC(NC3CCCCC3)=NC=C2)=NC(N4CCNCC4)=C1

Shipping

Room temperature in continental US; may vary elsewhere.

Storage

4°C, sealed storage, away from moisture and light

*In solvent : -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture and light)

Purity & Documentation
References
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BPKDi Related Classifications

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Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

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Product Name:
BPKDi
Cat. No.:
HY-118052
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