1116235-97-2
1116235-97-2
Chemical Structure
GSK1838705A
- CAS No.: 1116235-97-2
- Formula:C27H29FN8O3
- Molecular Weight:532.57
IUPAC Name: 2-((2-((1-(dimethylglycyl)-5-methoxyindolin-6-yl)amino)-7H-pyrrolo[2,3-d]pyrimidin-4-yl)amino)-6-fluoro-N-methylbenzamide
InChIKey: HZTYDQRUAWIZRE-UHFFFAOYSA-N
SMILES: FC1=C(C(NC)=O)C(NC2=C3C(NC=C3)=NC(NC4=CC5=C(CCN5C(CN(C)C)=O)C=C4OC)=N2)=CC=C1
Biological Activity: GSK1838705A is a potent and reversible IGF-IR and the insulin receptor inhibitor with IC50s of 2.0 and 1.6 nM, respectively. It also inhibits ALK with an IC50 of 0.5 nM.
| Cat. No. | Product Name | Purity | Description | Pricing | |||||||||||||||||||
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GSK1838705A | 99.58% | GSK1838705A is a potent and reversible IGF-IR and the insulin receptor inhibitor with IC50s of 2.0 and 1.6 nM, respectively. It also inhibits ALK with an IC50 of 0.5 nM. | ||||||||||||||||||||
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Structural Analogs
-
Similarity Score 0.69
HY-118046GSK2163632A -
Similarity Score 0.69
HY-145110IGF-1R inhibitor-2 -
Similarity Score 0.66
HY-164397XMU-MP-5 -
Similarity Score 0.60
HY-146792PLK1-IN-4 -
Similarity Score 0.60
HY-150022GRK5-IN-4 -
Similarity Score 0.57
HY-150021GRK5-IN-3 -
Similarity Score 0.54
HY-179679FAK-IN-29 -
Similarity Score 0.53
HY-149232HPK1-IN-35 -
Similarity Score 0.50
HY-145109HPK1-IN-20 -
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