113-59-7
113-59-7
Chemical Structure
Chlorprothixene
- CAS No.: 113-59-7
- Formula:C18H18ClNS
- Molecular Weight:315.86
IUPAC Name: (Z)-3-(2-chloro-9H-thioxanthen-9-ylidene)-N,N-dimethylpropan-1-amine
InChIKey: WSPOMRSOLSGNFJ-AUWJEWJLSA-N
SMILES: CN(C)CC/C=C1C2=C(SC3=C\1C=CC=C3)C=CC(Cl)=C2
Biological Activity: Chlorprothixene is a dopamine and histamine receptors antagonist with Kis of 18 nM, 2.96 nM, 4.56 nM, 9 nM and 3.75 nM for hD1, hD2, hD3, hD5 and hH1 receptors, respectively. Antipsychotic activity[1].
| Cat. No. | Product Name | Purity | Description | Pricing | |||||||||||||||||||
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Chlorprothixene | 99.87% | Chlorprothixene is a dopamine and histamine receptors antagonist with Kis of 18 nM, 2.96 nM, 4.56 nM, 9 nM and 3.75 nM for hD1, hD2, hD3, hD5 and hH1 receptors, respectively. Antipsychotic activity. | ||||||||||||||||||||
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Chlorprothixene (Standard) | ≥98% | Chlorprothixene (Standard) is the analytical standard of Chlorprothixene. This product is intended for research and analytical applications. Chlorprothixene is a dopamine and histamine receptors antagonist with Kis of 18 nM, 2.96 nM, 4.56 nM, 9 nM and 3.75 nM for hD1, hD2, hD3, hD5 and hH1 receptors, respectively. Antipsychotic activity. | ||||||||||||||||||||
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Zotepine | 99.80% | Zotepine, an antipsychotic agent, is a potent antagonist of 5-HT2A, 5-HT2C, Histamine H1, α1-adrenergic and Dopamine D2 receptors, with Kds of 2.6 nM, 3.2 nM, 3.3 nM, 7.3 nM and 8 nM, respectively. Zotepine exhibits antidepressive and anxiolytic effects in vivo. | ||||||||||||||||||||
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Dothiepin | 98.50% | Dothiepin (Dosulepin; Dothep) is an antidepressant agent with sedative/anxiolytic activity. Dothiepin is an inhibitor preferring of noradrenaline uptake than serotonin uptake. Dothiepin facilitates noradrenergic neurotransmission via inhibiting the neuronal uptake. Dothiepin is also an antagonist of histamine H1-receptor without cardiotoxicity. Dothiepin exhibits significant analgesic activity in psychogenic facial pain，idiopathic fibromyalgia syndrome or rheumatoid arthritis. | ||||||||||||||||||||
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Chlorprothixene-d3 | Chlorprothixene-d3 is the deuterium labeled Chlorprothixene Ep Impurity F (HY-Z16039). | |||||||||||||||||||||
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(E)-Dothiepin hydrochloride | (E)-Dothiepin ((E)-Dosulepin;(E)-Dothep) hydrochloride is an antidepressant agent with sedative/anxiolytic activity. (E)-Dothiepin hydrochloride is an inhibitor preferring of noradrenaline uptake than serotonin uptake. (E)-Dothiepin hydrochloride facilitates noradrenergic neurotransmission via inhibiting the neuronal uptake. (E)-Dothiepin hydrochloride is also an antagonist of histamine H1-receptor without cardiotoxicity. (E)-Dothiepin hydrochloride exhibits significant analgesic activity in psychogenic facial pain，idiopathic fibromyalgia syndrome or rheumatoid arthritis. | |||||||||||||||||||||
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Zuclopenthixol | 98.08% | Zuclopenthixol ((Z)-Clopenthixol) is a thioxanthene derivative which acts as a mixed dopamine D1/D2 receptor antagonist. | ||||||||||||||||||||
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Clopenthixol | 98.94% | Clopenthixol is a thiaquinoline compound with inhibitory effects similar to those of phenothiazine antipsychotics. Clopenthixol is an antagonist of D1 and D2 dopamine receptors. Clopenthixol is mainly used to suppress schizophrenia and other mental disorders. | ||||||||||||||||||||
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trans-Clopenthixol dihydrochloride | 99.98% | trans-Clopenthixol ((E)-Clopenthixol) dihydrochloride is an antibiotic agent, without neuroleptic effect. trans-Clopenthixol dihydrochloride can be used to inhibit Pseudomonas aeruginosa and Plasmodium falciparum in vitro. | ||||||||||||||||||||
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trans-Clopenthixol | 99.40% | trans-Clopenthixol ((E)-Clopenthixol) is an antibiotic, without neuroleptic effect. trans-Clopenthixol can be used to inhibit Pseudomonas aeruginosa and Plasmodium falciparum in vitro. | ||||||||||||||||||||
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Chlorprothixene hydrochloride (Standard) | ≥98% | Chlorprothixene (hydrochloride) (Standard) is the analytical standard of Chlorprothixene (hydrochloride). This product is intended for research and analytical applications. Chlorprothixene hydrochloride is a dopamine and histamine receptors antagonist with Kis of 18 nM, 2.96 nM, 4.56 nM, 9 nM and 3.75 nM for hD1, hD2, hD3, hD5 and hH1 receptors, respectively. Antipsychotic activity. | ||||||||||||||||||||
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(E/Z)-Chlorprothixene-d6 hydrochloride | (E/Z)-Chlorprothixene-d6 hydrochloride is the deuterium labeled (E/Z)-Chlorprothixene hydrochloride. | |||||||||||||||||||||
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