1151668-24-4
1151668-24-4
Chemical Structure
BNS-22
- CAS No.: 1151668-24-4
- Formula:C24H25NO5
- Molecular Weight:407.46
IUPAC Name: 5,7-dimethoxy-4-propyl-8-(1,2,3,4-tetrahydroquinoline-1-carbonyl)-2H-chromen-2-one
InChIKey: LRPUQCTZOSTSGL-UHFFFAOYSA-N
SMILES: O=C1C=C(CCC)C2=C(OC)C=C(OC)C(C(N3CCCC4=C3C=CC=C4)=O)=C2O1
Biological Activity:
BNS-22 is a DNA topoisomerase II (TOP2) catalytic inhibitor with the IC50 values of 2.8 μM and 0.42 μM for human TOP2α and TOP2β, respectively. BNS-22 induces abnormal division and has anti-proliferative activity[1].
| Cat. No. | Product Name | Purity | Description | Pricing | |||||||||||||||||||
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BNS-22 | 99.50% | BNS-22 is a DNA topoisomerase II (TOP2) catalytic inhibitor with the IC50 values of 2.8 μM and 0.42 μM for human TOP2α and TOP2β, respectively. BNS-22 induces abnormal division and has anti-proliferative activity. |
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Structural Analogs
-
Similarity Score 0.69
HY-174374Topobexin -
Similarity Score 0.50
HY-120923GUT-70 -
Similarity Score 0.50
HY-124828CMLD-2 -
Similarity Score 0.49
HY-129338CID 7309015 -
Similarity Score 0.49
HY-118279KSCM-1 -
Similarity Score 0.49
HY-19225AEnsaculin free base -
Similarity Score 0.49
HY-D2732NFC nitro probe 1 -
Similarity Score 0.48
HY-N19788Cyclomammein -
Similarity Score 0.48
HY-19225Ensaculin -
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