1197953-54-0
Chemical Structure
Brigatinib
Synonym(s): AP-26113
- CAS 番号: 1197953-54-0
- Formula:C29H39ClN7O2P
- Molecular Weight:584.09
IUPAC Name: (2-((5-chloro-2-((2-methoxy-4-(4-(4-methylpiperazin-1-yl)piperidin-1-yl)phenyl)amino)pyrimidin-4-yl)amino)phenyl)dimethylphosphine oxide
InChIKey: AILRADAXUVEEIR-UHFFFAOYSA-N
SMILES: CN1CCN(C2CCN(C3=CC=C(NC4=NC=C(Cl)C(NC5=CC=CC=C5P(C)(C)=O)=N4)C(OC)=C3)CC2)CC1
Biological Activity: Brigatinib (AP-26113) is a highly potent, selective and orally active ALK inhibitor, with an IC50 of 0.6 nM. Brigatinib can be used for research of NSCLC[1].
| 製品番号 | 製品名 | 純度 | 製品説明 | Pricing | |||||||||||||||||||
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Brigatinib | 99.97% | Brigatinib (AP-26113) is a highly potent, selective and orally active ALK inhibitor, with an IC50 of 0.6 nM. Brigatinib can be used for research of NSCLC. | ||||||||||||||||||||
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Brigatinib (Standard) | ≥98% | Brigatinib (Standard) is the analytical standard of Brigatinib. This product is intended for research and analytical applications. Brigatinib (AP-26113) is a highly potent, selective and orally active ALK inhibitor, with an IC50 of 0.6 nM. Brigatinib can be used for research of NSCLC. | ||||||||||||||||||||
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Brigatinib-13C6 | Brigatinib-13C6 is the 13C-labeled Brigatinib. Brigatinib (AP-26113) is a highly potent and selective ALK inhibitor, with an IC50 of 0.6 nM. | |||||||||||||||||||||
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Brigatinib-d11 | Brigatinib-d11 (AP-26113-d11) is deuterium labeled Brigatinib. Brigatinib (AP-26113) is a highly potent, selective and orally active ALK inhibitor, with an IC50 of 0.6 nM. Brigatinib can be used for research of NSCLC. | |||||||||||||||||||||
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-
Similarity Score 0.91
HY-150910Brigatinib C -
Similarity Score 0.84
HY-12973ALK-IN-13 -
Similarity Score 0.83
HY-108230ALK-IN-12 -
Similarity Score 0.83
HY-13464ALK-IN-1 -
Similarity Score 0.82
HY-145574Iruplinalkib -
Similarity Score 0.79
HY-153974BBT-176 -
Similarity Score 0.79
HY-182057ALK degrader 4 -
Similarity Score 0.78
HY-180922EGFR kinase-IN-8 -
Similarity Score 0.78
HY-10192RNVP-TAE 684 (Standard) -
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