1197953-54-0
1197953-54-0
Chemical Structure
Brigatinib
Synonym(s): AP-26113
- CAS No.: 1197953-54-0
- Formula:C29H39ClN7O2P
- Molecular Weight:584.09
IUPAC Name: (2-((5-chloro-2-((2-methoxy-4-(4-(4-methylpiperazin-1-yl)piperidin-1-yl)phenyl)amino)pyrimidin-4-yl)amino)phenyl)dimethylphosphine oxide
InChIKey: AILRADAXUVEEIR-UHFFFAOYSA-N
SMILES: CN1CCN(C2CCN(C3=CC=C(NC4=NC=C(Cl)C(NC5=CC=CC=C5P(C)(C)=O)=N4)C(OC)=C3)CC2)CC1
Biological Activity: Brigatinib (AP-26113) is a highly potent, selective and orally active ALK inhibitor, with an IC50 of 0.6 nM. Brigatinib can be used for research of NSCLC[1].
| Cat. No. | Product Name | Purity | Description | Pricing | |||||||||||||||||||
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Brigatinib | 99.97% | Brigatinib (AP-26113) is a highly potent, selective and orally active ALK inhibitor, with an IC50 of 0.6 nM. Brigatinib can be used for research of NSCLC. | ||||||||||||||||||||
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Brigatinib (Standard) | ≥98% | Brigatinib (Standard) is the analytical standard of Brigatinib. This product is intended for research and analytical applications. Brigatinib (AP-26113) is a highly potent, selective and orally active ALK inhibitor, with an IC50 of 0.6 nM. Brigatinib can be used for research of NSCLC. | ||||||||||||||||||||
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Brigatinib-13C6 | Brigatinib-13C6 is the 13C-labeled Brigatinib. Brigatinib (AP-26113) is a highly potent and selective ALK inhibitor, with an IC50 of 0.6 nM. | |||||||||||||||||||||
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Brigatinib-d11 | Brigatinib-d11 (AP-26113-d11) is deuterium labeled Brigatinib. Brigatinib (AP-26113) is a highly potent, selective and orally active ALK inhibitor, with an IC50 of 0.6 nM. Brigatinib can be used for research of NSCLC. | |||||||||||||||||||||
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References
