1198-69-2
Chemical Structure
D-Glucono-1,4-lactone
- CAS No.: 1198-69-2
- Formula:C6H10O6
- Molecular Weight:178.14
IUPAC Name: (3R,4R,5R)-5-((R)-1,2-dihydroxyethyl)-3,4-dihydroxydihydrofuran-2(3H)-one
InChIKey: SXZYCXMUPBBULW-TXICZTDVSA-N
SMILES: OC[C@H]([C@]1([H])[C@@H]([C@H](C(O1)=O)O)O)O
Biological Activity: D-Glucono-1,4-lactone is a derivative of D-gluconic acid (HY-Y0569C). D-Glucono-1,4-lactone can be isolated from fruits, vegetables, honey, kombucha and wine. D-Glucono-1,4-lactone inhibits thrombin-induced arachidonic acid peroxidation and platelet activation. D-Glucono-1,4-lactone reduces superoxide anion production in thrombin-activated platelets. D-Glucono-1,4-lactone exerts antioxidant activity on platelets under oxidative stress conditions and prevents excessive platelet activation through antioxidant mechanisms. D-Glucono-1,4-lactone can be used in research related to cardiovascular diseases[1][2].
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D-Glucono-1,4-lactone | D-Glucono-1,4-lactone is a derivative of D-gluconic acid (HY-Y0569C). D-Glucono-1,4-lactone can be isolated from fruits, vegetables, honey, kombucha and wine. D-Glucono-1,4-lactone inhibits thrombin-induced arachidonic acid peroxidation and platelet activation. D-Glucono-1,4-lactone reduces superoxide anion production in thrombin-activated platelets. D-Glucono-1,4-lactone exerts antioxidant activity on platelets under oxidative stress conditions and prevents excessive platelet activation through antioxidant mechanisms. D-Glucono-1,4-lactone can be used in research related to cardiovascular diseases. | |||||||||||||||||||||
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References
- [1]. Saluk-Juszczak J, et al. A comparative study of antioxidative activity of calcium-D-glucarate, sodium-D-gluconate and D-glucono-1,4-lactone in a human blood platelet model. Platelets. 2010;21(8):632-40. [Content Brief]
- [2]. Ashry E S H E, et al. MAOS of D‐gluconic acid, D‐glucono‐1, 4‐and 1, 5‐lactones, esters, hydrazides, and benzimidazoles thereof[J]. Journal of Carbohydrate Chemistry, 2007, 26(5-6): 329-338.
