120406-34-0
Chemical Structure
Jionoside D
- CAS No.: 120406-34-0
- Formula:C30H38O15
- Molecular Weight:638.61
IUPAC Name: (2R,3R,4R,5R,6R)-5-hydroxy-6-(3-hydroxy-4-methoxyphenethoxy)-2-(hydroxymethyl)-4-(((2S,3R,4R,5R,6S)-3,4,5-trihydroxy-6-methyltetrahydro-2H-pyran-2-yl)oxy)tetrahydro-2H-pyran-3-yl (E)-3-(3,4-dihydroxyphenyl)acrylate
InChIKey: WKQLGHCWJNLUKK-CPPDSBOHSA-N
SMILES: O[C@@H]1[C@@H](O)[C@@H](O)[C@@](O[C@@H]2[C@@H](O)[C@H](OCCC3=CC=C(OC)C(O)=C3)O[C@H](CO)[C@H]2OC(/C=C/C4=CC=C(O)C(O)=C4)=O)([H])O[C@H]1C
Biological Activity: Jionoside D is a hydroxycinnamic acid ester with antioxidant property. Jionoside D has scavenging activity of intracellular reactive oxygen species (ROS) and of DPPH radical, and lipid peroxidation inhibitory activity. Jionoside D reduces the apoptotic cells induced by H2O2 in V79-4 cells. Jionoside D increases the activities of cellular antioxidant enzymes, SOD and catalase[1][2].
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Jionoside D | Jionoside D is a hydroxycinnamic acid ester with antioxidant property. Jionoside D has scavenging activity of intracellular reactive oxygen species (ROS) and of DPPH radical, and lipid peroxidation inhibitory activity. Jionoside D reduces the apoptotic cells induced by H2O2 in V79-4 cells. Jionoside D increases the activities of cellular antioxidant enzymes, SOD and catalase. | |||||||||||||||||||||
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References
- [1]. Sasaki H, et al. Hydroxycinnamic acid esters of phenethylalcohol glycosides from Rehmannia glutinosa var. Purpurea[J]. Phytochemistry, 1989, 28(3):875-879.
- [2]. Chae S, et al. Antioxidant activity of jionoside D from Clerodendron trichotomum. Biol Pharm Bull. 2004 Oct;27(10):1504-8. [Content Brief]
