1216739-35-3
Chemical Structure
Bumetanide-d5
- CAS No.: 1216739-35-3
- Formula:C17H15D5N2O5S
- Molecular Weight:369.45
IUPAC Name: 3-(butylamino)-4-(phenoxy-d5)-5-sulfamoylbenzoic acid
InChIKey: MAEIEVLCKWDQJH-UPKDRLQUSA-N
SMILES: O=C(O)C1=CC(NCCCC)=C(OC2=C([2H])C([2H])=C([2H])C([2H])=C2[2H])C(S(=O)(N)=O)=C1
Biological Activity: Bumetanide-d5 is a deuterium labeled Bumetanide. Bumetanide is a selective Na+-K+-Cl- (NKCC1) inhibitor, weakly inhibits NKCC2, with ?IC50s of 0.68 and 4.0 μM for hNKCC1A and hNKCC2A, respectively[1].
| Cat. No. | 상품명 | Purity | 제품 설명 | Pricing | |||||||||||||||||||
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Bumetanide-d5 | 98.55% | Bumetanide-d5 is a deuterium labeled Bumetanide. Bumetanide is a selective Na+-K+-Cl- (NKCC1) inhibitor, weakly inhibits NKCC2, with ?IC50s of 0.68 and 4.0 μM for hNKCC1A and hNKCC2A, respectively. | ||||||||||||||||||||
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Bumetanide (Standard) | 99.97% | Bumetanide (Standard) is the analytical standard of Bumetanide. This product is intended for research and analytical applications. Bumetanide (Ro 10-6338; PF 1593), a highly potent loop diuretic, is a Na+-K+-Cl+ cotransporter (NKCC) blocker. Bumetanide is a selective NKCC1 inhibitor, but also inhibits NKCC2, with IC50s of 0.68 μM and 4.0 μM for hNKCC1A and hNKCC2A, respectively. | ||||||||||||||||||||
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Bumetanide solution | Bumetanide solution is mainly composed of Bumetanide (HY-17468). Bumetanide (Ro 10-6338; PF 1593), a highly potent loop diuretic, is a Na+-K+-Cl+ cotransporter (NKCC) blocker. Bumetanide is a selective NKCC1 inhibitor, but also inhibits NKCC2, with IC50s of 0.68 μM and 4.0 μM for hNKCC1A and hNKCC2A, respectively. | |||||||||||||||||||||
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Bumetanide | 99.90% | Bumetanide (Ro 10-6338; PF 1593), a highly potent loop diuretic, is a Na+-K+-Cl+ cotransporter (NKCC) blocker. Bumetanide is a selective NKCC1 inhibitor, but also inhibits NKCC2, with IC50s of 0.68 μM and 4.0 μM for hNKCC1A and hNKCC2A, respectively. | ||||||||||||||||||||
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Similarity Score 0.93
HY-Z9172Bumetanide impurity 5 -
Similarity Score 0.88
HY-17468ABumetanide sodium -
Similarity Score 0.85
HY-101875Bumetanide impurity 7 -
Similarity Score 0.84
HY-17468S1Bumetanide-d5 Butyl Ester -
Similarity Score 0.82
HY-Z7981RBumetanide impurity 2 (Standard) -
Similarity Score 0.75
HY-Z7980Bumetanide impurity 1 -
Similarity Score 0.73
HY-119816RPiretanide (Standard) -
Similarity Score 0.69
HY-Z7979Bumetanide impurity 3 -
Similarity Score 0.65
HY-119816SPiretanide-d4 -
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