Bumetanide-d5
Based on 1 Customer Validation
Bumetanide-d5 is a deuterium labeled Bumetanide. Bumetanide is a selective Na+-K+-Cl- (NKCC1) inhibitor, weakly inhibits NKCC2, with ?IC50s of 0.68 and 4.0 μM for hNKCC1A and hNKCC2A, respectively.
For research use only. We do not sell to patients.
- Purity: 99.82%
- CAS No.: 1216739-35-3
- Formula: C17H15D5N2O5S
- Molecular Weight:369.45
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Storage:Powder -20°C, 3 years ; In solvent -80°C, 6 months , -20°C, 1 month
Biological Activity
1. This compound can be used as a tracer
2. This compound can be used as an internal standard for quantitative analysis by NMR, GC-MS, or LC-MS.
Chemical Information
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CAS No. 1216739-35-3
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Unlabeled Cas 28395-03-1
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Appearance Solid
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Molecular Weight 369.45
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Formula C17H15D5N2O5S
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Color White to off-white
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SMILES
O=C(O)C1=CC(NCCCC)=C(OC2=C([2H])C([2H])=C([2H])C([2H])=C2[2H])C(S(=O)(N)=O)=C1
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
Powder -20°C 3 years In solvent -80°C 6 months -20°C 1 month
Solvent & Solubility
DMF : ≥ 33 mg/mL (89.32 mM)
DMSO : ≥ 25 mg/mL (67.67 mM; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)
Ethanol : ≥ 14 mg/mL (37.89 mM)
* "≥" means soluble, but saturation unknown.
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
Purity & Documentation
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Data Sheet (276 KB)
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SDS (252 KB)
- English - EN (252 KB)
- Français - FR (252 KB)
- Deutsch - DE (252 KB)
- Norwegian - NO (252 KB)
- Español - ES (252 KB)
- Swedish - SV (252 KB)
- Italian - IT (252 KB)
- Korean - KR (252 KB)
- Portuguese - PT (252 KB)
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Handling Instructions (2659 KB)
References
Complete Stock Solution Preparation Table
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
| Optional Solvent | Concentration Solvent Mass | 1 mg | 5 mg | 10 mg | 25 mg |
|---|---|---|---|---|---|
| Ethanol / DMSO / DMF | 1 mM | 2.7067 mL | 13.5336 mL | 27.0673 mL | 67.6682 mL |
| 5 mM | 0.5413 mL | 2.7067 mL | 5.4135 mL | 13.5336 mL | |
| 10 mM | 0.2707 mL | 1.3534 mL | 2.7067 mL | 6.7668 mL | |
| 15 mM | 0.1804 mL | 0.9022 mL | 1.8045 mL | 4.5112 mL | |
| 20 mM | 0.1353 mL | 0.6767 mL | 1.3534 mL | 3.3834 mL | |
| 25 mM | 0.1083 mL | 0.5413 mL | 1.0827 mL | 2.7067 mL | |
| 30 mM | 0.0902 mL | 0.4511 mL | 0.9022 mL | 2.2556 mL | |
| DMSO / DMF | 40 mM | 0.0677 mL | 0.3383 mL | 0.6767 mL | 1.6917 mL |
| 50 mM | 0.0541 mL | 0.2707 mL | 0.5413 mL | 1.3534 mL | |
| 60 mM | 0.0451 mL | 0.2256 mL | 0.4511 mL | 1.1278 mL | |
| DMF | 80 mM | 0.0338 mL | 0.1692 mL | 0.3383 mL | 0.8459 mL |