123464-89-1
123464-89-1
Chemical Structure
PNU-282987
- CAS No.: 123464-89-1
- Formula:C14H18Cl2N2O
- Molecular Weight:301.21
IUPAC Name: (R)-4-chloro-N-(quinuclidin-3-yl)benzamide hydrochloride
InChIKey: HSEQUIRZHDYOIX-ZOWNYOTGSA-N
SMILES: O=C(C1=CC=C(C=C1)Cl)N[C@H]2CN3CCC2CC3.[H]Cl
Biological Activity: PNU-282987 is a potent α7 nicotinic acetylcholine receptor (nAChR) agonist with an EC50 of 154 nM. PNU-282987 is also a functional antagonist of the 5-HT3 receptor with an IC50 of 4541 nM. PNU-282987 can be used for the research of central and peripheral nervous systems[1].
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PNU-282987 | 99.94% | PNU-282987 is a potent α7 nicotinic acetylcholine receptor (nAChR) agonist with an EC50 of 154 nM. PNU-282987 is also a functional antagonist of the 5-HT3 receptor with an IC50 of 4541 nM. PNU-282987 can be used for the research of central and peripheral nervous systems. | ||||||||||||||||||||
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