123653-11-2
Chemical Structure
NS-398
- CAS No.: 123653-11-2
- Formula:C13H18N2O5S
- Molecular Weight:314.36
IUPAC Name: N-(2-(cyclohexyloxy)-4-nitrophenyl)methanesulfonamide
InChIKey: KTDZCOWXCWUPEO-UHFFFAOYSA-N
SMILES: CS(=O)(NC1=CC=C([N+]([O-])=O)C=C1OC2CCCCC2)=O
Biological Activity: NS-398 is a non-steroidal an-inflammatory agent with analgesic and antipyretic effects, and selectively inhibits prostaglandin G/H synthase 2/cyclooxygenase 2 (COX-2) activity, with an IC50 of 3.8 μM, and has no effect on COX-1 at 100 μM.
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NS-398 | 99.71% | NS-398 is a non-steroidal an-inflammatory agent with analgesic and antipyretic effects, and selectively inhibits prostaglandin G/H synthase 2/cyclooxygenase 2 (COX-2) activity, with an IC50 of 3.8 μM, and has no effect on COX-1 at 100 μM. | ||||||||||||||||||||
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NS-398 (Standard) | ≥98% | NS-398 (Standard) is the analytical standard of NS-398. This product is intended for research and analytical applications. NS-398 is a non-steroidal an-inflammatory agent with analgesic and antipyretic effects, and selectively inhibits prostaglandin G/H synthase 2/cyclooxygenase 2 (COX-2) activity, with an IC50 of 3.8 μM, and has no effect on COX-1 at 100 μM. | ||||||||||||||||||||
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Keywords