1246820-06-3
Chemical Structure
4-Methylamino antipyrine-d3-1
- CAS No.: 1246820-06-3
- Formula:C12H12D3N3O
- Molecular Weight:220.29
IUPAC Name: 1,5-dimethyl-4-((methyl-d3)amino)-2-phenyl-1,2-dihydro-3H-pyrazol-3-one
InChIKey: JILCEWWZTBBOFS-BMSJAHLVSA-N
SMILES: O=C1C(NC([2H])([2H])[2H])=C(N(N1C2=CC=CC=C2)C)C
Biological Activity: 4-Methylamino antipyrine-d3-1 is the deuterium labeled 4-Methylamino antipyrine-1. 4-Methylamino antipyrine is an active metabolite of Metamizole. Metamizole is a pyrazolone non-steroidal anti-inflammatory drug (NSAID) and inhibits COX. Metamizole is an nonopioid analgesic agent and can be used for pain and fever[1][2][3]. 4-Methylamino antipyrine has analgesic, antipyretic, and relatively weak antiinflammatory properties[2].
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4-Methylamino antipyrine-d3-1 | 4-Methylamino antipyrine-d3-1 is the deuterium labeled 4-Methylamino antipyrine-1. 4-Methylamino antipyrine is an active metabolite of Metamizole. Metamizole is a pyrazolone non-steroidal anti-inflammatory drug (NSAID) and inhibits COX. Metamizole is an nonopioid analgesic agent and can be used for pain and fever. 4-Methylamino antipyrine has analgesic, antipyretic, and relatively weak antiinflammatory properties. | |||||||||||||||||||||
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4-Methylamino antipyrine (Standard) | ≥98% | 4-Methylamino antipyrine (Standard) is the analytical standard of 4-Methylamino antipyrine. This product is intended for research and analytical applications. 4-Methylamino antipyrine is an active metabolite of Metamizole. Metamizole is a pyrazolone non-steroidal anti-inflammatory drug (NSAID) and inhibits COX. Metamizole is an nonopioid analgesic agent and can be used for pain and fever. 4-Methylamino antipyrine has analgesic, antipyretic, and relatively weak antiinflammatory properties. | ||||||||||||||||||||
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4-Methylamino antipyrine | 99.18% | 4-Methylamino antipyrine is an active metabolite of Metamizole. Metamizole is a pyrazolone non-steroidal anti-inflammatory drug (NSAID) and inhibits COX. Metamizole is an nonopioid analgesic agent and can be used for pain and fever. 4-Methylamino antipyrine has analgesic, antipyretic, and relatively weak antiinflammatory properties. | ||||||||||||||||||||
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Similarity Score 0.98
HY-135731A4-Methylamino antipyrine hydrochloride -
Similarity Score 0.87
HY-B1137RRamifenazone (Standard) -
Similarity Score 0.87
HY-133588R4-Formylaminoantipyrine (Standard) -
Similarity Score 0.86
HY-W2685424-Acetylaminoantipyrine -
Similarity Score 0.82
HY-W1009904-Aminoantipyrine hydrochloride -
Similarity Score 0.79
HY-W268542S14-Acetylaminoantipyrine-d3 -
Similarity Score 0.77
HY-128480Sulfamidopyrine sodium salt -
Similarity Score 0.74
HY-B1137SRamifenazone-d7 -
Similarity Score 0.73
HY-148147Metamizole -
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References
- [1]. Burmańczuk A, et al. Pharmacokinetic investigations of the marker active metabolites 4-methylamino-antipyrine and 4-amino-antipyrine after intramuscular injection of metamizole in healthy piglets. J Vet Pharmacol Ther. 2016 Dec;39(6):616-620. [Content Brief]
- [2]. Ariza A, et al. Pyrazolones metabolites are relevant for identifying selective anaphylaxis to metamizole. Sci Rep. 2016 Mar 31;6:23845. [Content Brief]
- [3]. Campos C1, et al. Regulation of cyclooxygenase activity by metamizol. Eur J Pharmacol. 1999 Aug 13;378(3):339-47. [Content Brief]
