Metamizole
Based on 2 publication(s) in Google Scholar
Metamizol (Methamizole) is an anti-thyroid agent, which blocks thyroid hormone production from the thyroid gland. Metamizol can cause hepatotoxicity.
It is advisable to consider the stable salt form (Metamizole sodium) that retains the same biological activity.
For research use only. We do not sell to patients.
- CAS No.: 50567-35-6
- Formula: C13H17N3O4S
- Molecular Weight:311.36
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Storage:
Please store the product under the recommended conditions in the Certificate of Analysis.
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Publications Citing Use of MedChemExpress (MCE) Metamizole
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Biological Activity
Description
In Vivo
Metamizo (100 mg/kg; i.p.; once; male Swiss albino mice) causes a decrease in hepatic glutathione (GSH) contents[1].
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
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Animal Model:Male Swiss albino mice (6 weeks old, 25-40 g)[1]
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Dosage:100 mg/kg
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Administration:Intraperitoneal injection; once
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Result:Increased serum ALT level at 5 hours and the maximum serum ALT levels occurred at 5 hours.
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Animal Model:Male Swiss albino mice (6 weeks old, 25-40 g)[1]
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Dosage:100 mg/kg
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Administration:Intraperitoneal injection; once
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Result:Induced reduction in hepatic glutathione (GSH) content in mice.
Chemical Information
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CAS No. 50567-35-6
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Molecular Weight 311.36
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Formula C13H17N3O4S
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SMILES
O=C1C(N(CS(=O)(O)=O)C)=C(C)N(C)N1C2=CC=CC=C2
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Synonyms
Dipyrone free base; Methamizole
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
Please store the product under the recommended conditions in the Certificate of Analysis.
Publications (2)
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Journal Impact Factor
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Most Recent
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Int J Biol Macromol
Reticuline isomerase AKR1B1 with aldo-keto reductase activity and detoxification function from the insect Blaps rhynchopetera. [Abstract]2026 Mar:352:151224. PMID: 41791543 -
Animal Model Exp Med
Experimental study of a novel mouse model of tibial shaft fracture combined with blunt chest trauma. [Abstract]2025 Apr;8(4):696-706. PMID: 38225728
Purity & Documentation
References
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
Metamizole Related Classifications
HY-148147 Related Classifications
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