1253584-84-7
1253584-84-7
Chemical Structure
NMS-E973
- CAS No.: 1253584-84-7
- Formula:C22H22N4O7
- Molecular Weight:454.43
IUPAC Name: 5-(2,4-dihydroxy-6-(4-nitrophenoxy)phenyl)-N-(1-methylpiperidin-4-yl)isoxazole-3-carboxamide
InChIKey: YLQODGGPIHWTHR-UHFFFAOYSA-N
SMILES: O=C(C1=NOC(C2=C(OC3=CC=C([N+]([O-])=O)C=C3)C=C(O)C=C2O)=C1)NC4CCN(C)CC4
Biological Activity: NMS-E973 is a potent and selective inhibitor of HSP90. NMS-E973 binds to the ATP binding site of Hsp90α with a DC50 of <10 nM. NMS-E973 is able to cross the blood-brain barrier (BBB). Antitumor efficacy[1].
| Cat. No. | 상품명 | Purity | 제품 설명 | Pricing | |||||||||||||||||||
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NMS-E973 | 99.61% | NMS-E973 is a potent and selective inhibitor of HSP90. NMS-E973 binds to the ATP binding site of Hsp90α with a DC50 of <10 nM. NMS-E973 is able to cross the blood-brain barrier (BBB). Antitumor efficacy. | ||||||||||||||||||||
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