125708-06-7
Chemical Structure
Lyciumin A
- CAS. Nr.: 125708-06-7
- Formula:C42H51N9O12
- Molecular Weight:873.91
IUPAC Name: (3S,6S,12S,15R,Z)-6-(hydroxymethyl)-15-((S)-3-(4-hydroxyphenyl)-2-((S)-1-((R)-5-oxopyrrolidine-2-carbonyl)pyrrolidine-2-carboxamido)propanamido)-12-isopropyl-5,8,11,14-tetraoxo-11H-4,7,10,13-tetraaza-1(1,3)-indolacyclopentadecaphane-3-carboxylic acid
InChIKey: IPOLXDNCMOVXCP-WUVUALGCSA-N
SMILES: O=C([C@@H](NC([C@@H](NC(CNC1=O)=O)CO)=O)CC2=CN(C3=C2C=CC=C3)[C@@H](NC([C@@H](NC([C@H]4N(CCC4)C([C@@H]5NC(CC5)=O)=O)=O)CC6=CC=C(C=C6)O)=O)C(N[C@H]1C(C)C)=O)O
Biological Activity: Lyciumin A, a cyclic octapeptide, exhibits inhibitory activity on proteases, renin and angiotensin-converting enzyme. Lyciumin A can be used for the research of hypertension[1][2].
| Art. -Nr. | Produktname | Reinheit | Beschreibung | Pricing | |||||||||||||||||||
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Lyciumin A | 98.59% | Lyciumin A, a cyclic octapeptide, exhibits inhibitory activity on proteases, renin and angiotensin-converting enzyme. Lyciumin A can be used for the research of hypertension. | ||||||||||||||||||||
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References
- [1]. Kersten RD, et, al. Gene-guided discovery and engineering of branched cyclic peptides in plants. Proc Natl Acad Sci U S A. 2018 Nov 13;115(46):E10961-E10969. [Content Brief]
- [2]. Rubin GM, et, al. Recent advances in the biosynthesis of RiPPs from multicore-containing precursor peptides. J Ind Microbiol Biotechnol. 2020 Oct;47(9-10):659-674. [Content Brief]
