127582-76-7
Chemical Structure
Fmoc-7-amino-heptanoic acid
- CAS No.: 127582-76-7
- Formula:C22H25NO4
- Molecular Weight:367.44
IUPAC Name: 7-((((9H-fluoren-9-yl)methoxy)carbonyl)amino)heptanoic acid
InChIKey: FRPYXTFBPCYALT-UHFFFAOYSA-N
SMILES: O=C(O)CCCCCCNC(OCC1C2=C(C3=C1C=CC=C3)C=CC=C2)=O
Biological Activity: Fmoc-7-amino-heptanoic acid is an alkane chain with terminal Fmoc-protected amine and carboxylic acid groups. Fmoc-7-amino-heptanoic acid can be used as a PROTAC linker in the synthesis of PROTACs. The Fmoc group can be deprotected under basic condition to obtain the free amine which can be used for further conjugations. The terminal carboxylic acid can react with primary amine groups in the presence of activators (e.g. EDC, or HATU) to form a stable amide bond.
| Cat. No. | Product Name | Purity | Description | Pricing | |||||||||||||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
|
|
Fmoc-7-amino-heptanoic acid | Fmoc-7-amino-heptanoic acid is an alkane chain with terminal Fmoc-protected amine and carboxylic acid groups. Fmoc-7-amino-heptanoic acid can be used as a PROTAC linker in the synthesis of PROTACs. The Fmoc group can be deprotected under basic condition to obtain the free amine which can be used for further conjugations. The terminal carboxylic acid can react with primary amine groups in the presence of activators (e.g. EDC, or HATU) to form a stable amide bond. | |||||||||||||||||||||
|
loading...
/
|
|||||||||||||||||||||||
Keywords
