127792-75-0
127792-75-0
Chemical Structure
CP 93129
- CAS 番号: 127792-75-0
- Formula:C12H13N3O
- Molecular Weight:215.25
IUPAC Name: 3-(1,2,3,6-tetrahydropyridin-4-yl)-1,4-dihydro-5H-pyrrolo[3,2-b]pyridin-5-one
InChIKey: PJYVGMRFPFNZCT-UHFFFAOYSA-N
SMILES: O=C1C=CC2=C(N1)C(C3=CCNCC3)=CN2
Biological Activity: CP 93129 is a potent and selective 5-HT1B agonist. CP 93129 has the potential for the research of Parkinson's disease[1][2].
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CP 93129 | CP 93129 is a potent and selective 5-HT1B agonist. CP 93129 has the potential for the research of Parkinson's disease. | |||||||||||||||||||||
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References
- [1]. Przegaliński E, et al. Effects of 5-HT1B receptor ligands microinjected into the accumbal shell or core on the cocaine-induced locomotor hyperactivity in rats. J Physiol Pharmacol. 2002 Sep;53(3):383-94. [Content Brief]
- [2]. Chadha A, et al. The 5HT(1B) receptor agonist, CP-93129, inhibits [(3)H]-GABA release from rat globus pallidus slices and reverses akinesia following intrapallidal injection in the reserpine-treated rat. Br J Pharmacol. 2000 Aug;130(8):1927-32. [Content Brief]
