1305115-80-3
Chemical Structure
PF-04957325
- CAS No.: 1305115-80-3
- Formula:C14H15F3N8OS
- Molecular Weight:400.38
IUPAC Name: (R)-3-((4-(thiazol-2-ylmethyl)morpholin-2-yl)methyl)-5-(trifluoromethyl)-3H-[1,2,3]triazolo[4,5-d]pyrimidin-7-amine
InChIKey: VNLPYEMGHGDRRZ-MRVPVSSYSA-N
SMILES: NC1=C(N=NN2C[C@H]3CN(CC4=NC=CS4)CCO3)C2=NC(C(F)(F)F)=N1
Biological Activity: PF-04957325 is a highly potent and selective PDE8 inhibitor, with IC50s of 0.7 nM and 0.3 nM for PDE8A and PDE8B, respectively.
| Cat. No. | Product Name | Purity | Description | Pricing | |||||||||||||||||||
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PF-04957325 | 99.55% | PF-04957325 is a highly potent and selective PDE8 inhibitor, with IC50s of 0.7 nM and 0.3 nM for PDE8A and PDE8B, respectively. | ||||||||||||||||||||
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-
Similarity Score 0.84
HY-135711PDE8B-IN-1 -
Similarity Score 0.84
HY-117848PDE8B-IN-1 hydrochloride -
Similarity Score 0.46
HY-145604Vicasinabin -
Similarity Score 0.45
HY-1524202-Trifluoromethyl adenosine -
Similarity Score 0.45
HY-175544anti-TNBC agent-10 -
Similarity Score 0.43
HY-121706PU-20F -
Similarity Score 0.41
HY-183539INCB191358 -
Similarity Score 0.41
HY-152461N6-(3-Trifluoromethylbenzyl)-3’-deoxyadenosine -
Similarity Score 0.41
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