13110-96-8
Chemical Structure
5-Acetylsalicylic acid
- CAS No.: 13110-96-8
- Formula:C9H8O4
- Molecular Weight:180.16
IUPAC Name: 5-acetyl-2-hydroxybenzoic acid
InChIKey: NZRDKNBIPVLNHA-UHFFFAOYSA-N
SMILES: O=C(O)C1=CC(C(C)=O)=CC=C1O
Biological Activity: 5-Acetylsalicylic acid is the derivate of Aspirin (HY-14654), with anti-inflammatory property. 5-Acetylsalicylic acid is the active metabolite of Sulfasalazine (HY-14655) and its production is regulated by beneficial bacteria in the gut but is confined to the intestinal tract. 5-Acetylsalicylic acid exhibits a mild cytotoxicity effect on B16F10 cells. 5-Acetylsalicylic acid can be used for the study of inflammatory bowel disease (IBD) such as ulcerative colitis (UC)[1][2][3].
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5-Acetylsalicylic acid | 99.69% | 5-Acetylsalicylic acid is the derivate of Aspirin (HY-14654), with anti-inflammatory property. 5-Acetylsalicylic acid is the active metabolite of Sulfasalazine (HY-14655) and its production is regulated by beneficial bacteria in the gut but is confined to the intestinal tract. 5-Acetylsalicylic acid exhibits a mild cytotoxicity effect on B16F10 cells. 5-Acetylsalicylic acid can be used for the study of inflammatory bowel disease (IBD) such as ulcerative colitis (UC). | ||||||||||||||||||||
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5-Acetylsalicylic acid (Standard) | 5-Acetylsalicylic acid (Standard) is the analytical standard of 5-Acetylsalicylic acid (HY-107831). This product is intended for research and analytical applications. 5-Acetylsalicylic acid is the derivate of Aspirin (HY-14654), with anti-inflammatory property. 5-Acetylsalicylic acid is the active metabolite of Sulfasalazine (HY-14655) and its production is regulated by beneficial bacteria in the gut but is confined to the intestinal tract. 5-Acetylsalicylic acid exhibits a mild cytotoxicity effect on B16F10 cells. 5-Acetylsalicylic acid can be used for the study of inflammatory bowel disease (IBD) such as ulcerative colitis (UC). | |||||||||||||||||||||
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References
- [1]. Lee HJ, et al. The influence of probiotic treatment on sulfasalazine metabolism in rat. Xenobiotica. 2012 Aug;42(8):791-7. [Content Brief]
- [2]. Islam A, et al. Cytotoxicity and apoptotic activity of novel organobismuth(V) and organoantimony(V) complexes in different cancer cell lines. Eur J Med Chem. 2016 Feb 15;109:254-67. [Content Brief]
- [3]. Ishimura A. Prescription of 5-acetylsalicylic Acid Formulations to Patients with Ulcerative Colitis in Japan. Applied Therapeutics. 2024;19:92-4.
