134036-52-5
134036-52-5
Chemical Structure
(E/Z)-AG490
Synonym(s): (E/Z)-Tyrphostin AG490; (E/Z)-Tyrphostin B42
- CAS No.: 134036-52-5
- Formula:C17H14N2O3
- Molecular Weight:294.30
IUPAC Name: (E)-N-benzyl-2-cyano-3-(3,4-dihydroxyphenyl)acrylamide
InChIKey: TUCIOBMMDDOEMM-RIYZIHGNSA-N
SMILES: O=C(NCC1=CC=CC=C1)/C(C#N)=C/C2=CC=C(O)C(O)=C2
Biological Activity: (E/Z)-AG490 ((E/Z)-Tyrphostin AG490) is a racemic compound of (E)-AG490 and (Z)-AG490 isomers. (E)-AG490 (HY-12000) is a tyrosine kinase inhibitor that inhibits EGFR, Stat-3 and JAK2/3.
| Cat. No. | Product Name | Purity | Description | Pricing | |||||||||||||||||||
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(E/Z)-AG490 | 99.71% | (E/Z)-AG490 ((E/Z)-Tyrphostin AG490) is a racemic compound of (E)-AG490 and (Z)-AG490 isomers. (E)-AG490 (HY-12000) is a tyrosine kinase inhibitor that inhibits EGFR, Stat-3 and JAK2/3. | ||||||||||||||||||||
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(E/Z)-AG490 (Standard) | ≥98% | (E/Z)-AG490 (Standard) is the analytical standard of (E/Z)-AG490 (HY-107459). This product is intended for research and analytical applications. (E/Z)-AG490 ((E/Z)-Tyrphostin AG490) is a racemic compound of (E)-AG490 and (Z)-AG490 isomers. (E)-AG490 (HY-12000) is a tyrosine Kinase inhibitor that inhibits EGFR, Stat-3 and JAK2/3. | ||||||||||||||||||||
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Structural Analogs
-
Similarity Score 1.00
HY-12000AG490 -
Similarity Score 0.86
HY-118084LS-104 -
Similarity Score 0.86
HY-15336AG 555 -
Similarity Score 0.84
HY-101007A(+)-Tyrphostin B44 -
Similarity Score 0.82
HY-101042AG-494 -
Similarity Score 0.78
HY-118143AG-1801 -
Similarity Score 0.77
HY-137786EGFR-IN-16 -
Similarity Score 0.75
HY-138688Cinnamyl-3,4-dihydroxy-α-cyanocinnamate -
Similarity Score 0.74
HY-114683KS370G -
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