1. JAK/STAT Signaling
    Protein Tyrosine Kinase/RTK
    Stem Cell/Wnt
    Epigenetics
  2. EGFR
    STAT
    JAK
  3. (E/Z)-AG490

(E/Z)-AG490 (Synonyms: (E/Z)-Tyrphostin AG490; (E/Z)-Tyrphostin B42)

Cat. No.: HY-107459 Purity: ≥96.0%
Handling Instructions

(E/Z)-AG490 ((E/Z)-Tyrphostin AG490) is a racemic compound of (E)-AG490 and (Z)-AG490 isomers. (E)-AG490 (HY-12000) is a tyrosine kinase inhibitor that inhibits EGFR, Stat-3 and JAK2/3.

For research use only. We do not sell to patients.

(E/Z)-AG490 Chemical Structure

(E/Z)-AG490 Chemical Structure

CAS No. : 134036-52-5

Size Price Stock Quantity
1 mg USD 90 In-stock
Estimated Time of Arrival: December 31
5 mg USD 150 In-stock
Estimated Time of Arrival: December 31
10 mg   Get quote  
50 mg   Get quote  

* Please select Quantity before adding items.

Customer Review

Based on 1 publication(s) in Google Scholar

Other Forms of (E/Z)-AG490:

Top Publications Citing Use of Products

View All EGFR Isoform Specific Products:

View All STAT Isoform Specific Products:

View All JAK Isoform Specific Products:

  • Biological Activity

  • Purity & Documentation

  • Customer Review

Description

(E/Z)-AG490 ((E/Z)-Tyrphostin AG490) is a racemic compound of (E)-AG490 and (Z)-AG490 isomers. (E)-AG490 (HY-12000) is a tyrosine kinase inhibitor that inhibits EGFR, Stat-3 and JAK2/3.

Molecular Weight

294.30

Formula

C₁₇H₁₄N₂O₃

CAS No.

134036-52-5

SMILES

O=C(NCC1=CC=CC=C1)/C(C#N)=C/C2=CC=C(O)C(O)=C2

Shipping

Room temperature in continental US; may vary elsewhere.

Storage
Powder -20°C 3 years
In solvent -80°C 6 months
-20°C 1 month

Purity: ≥96.0%

  • No file chosen (Maximum size is: 1024 Kb)
  • If you have published this work, please enter the PubMed ID.
  • Your name will appear on the site.
  • Molarity Calculator

  • Dilution Calculator

The molarity calculator equation

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

Mass   Concentration   Volume   Molecular Weight *
= × ×

The dilution calculator equation

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
× = ×
C1   V1   C2   V2

Keywords:

(E/Z)-AG490(E/Z)-Tyrphostin AG490 (E/Z)-Tyrphostin B42EGFRSTATJAKEpidermal growth factor receptorErbB-1HER1Janus kinasetyrosinekinase,EGFRStat-3JAK2/3Inhibitorinhibitorinhibit

Your Recently Viewed Products:

Inquiry Online

Your information is safe with us. * Required Fields.

Product Name

 

Salutation

Applicant Name *

 

Email address *

Phone number *

 

Organization name *

Department *

 

Requested quantity *

Country or Region *

     

Remarks

Bulk Inquiry

Inquiry Information

Product Name:
(E/Z)-AG490
Cat. No.:
HY-107459
Quantity:
MCE Japan Authorized Agent: