134564-82-2
Chemical Structure
Befloxatone
Synonym(s): MD-370503
- CAS No.: 134564-82-2
- Formula:C15H18F3NO5
- Molecular Weight:349.30
IUPAC Name: (R)-5-(methoxymethyl)-3-(4-((R)-4,4,4-trifluoro-3-hydroxybutoxy)phenyl)oxazolidin-2-one
InChIKey: IALVDLPLCLFBCF-CHWSQXEVSA-N
SMILES: O=C1O[C@@H](COC)CN1C2=CC=C(OCC[C@@H](O)C(F)(F)F)C=C2
Biological Activity: Befloxatone (MD-370503) is an orally active, selective and reversible inhibitor of Monoamine Oxidase A (MAO-A) (IC50=4 nM). Befloxatone increases the tissue level of monoamine, striatal dopamine and cortical norepinephrine. Befloxatone has antidepressant potential[1].
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Befloxatone | Befloxatone (MD-370503) is an orally active, selective and reversible inhibitor of Monoamine Oxidase A (MAO-A) (IC50=4 nM). Befloxatone increases the tissue level of monoamine, striatal dopamine and cortical norepinephrine. Befloxatone has antidepressant potential. | |||||||||||||||||||||
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Keywords